CV Lattes
Universidade Estadual de Campinas (UNICAMP). Instituto de Biologia (IB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Bachelor's degree in Pharmacy at Universidade Federal do Ceará (2010), where carried out activities with emphasis on Biochemistry and Hematology. PhD in Sciences (Biotechnology) by the Institute of Biomedical Sciences of the University of São Paulo (USP-2014), where developed a research project in the area of Physiology, focusing in Endocrine Physiology. Deep knowledge in several analyzes of mitochondrial function and insulin resistance during Doctorate training at the University of Maastricht - Netherlands (2012-2013). Post-doctorate at State University of Campinas (UNICAMP 2014-2015), developing a project focusing on Bioenergetics and Metabolism. During academic career, worked mainly in sub-areas involving fatty acids, obesity, insulin resistance, mitochondrial function, skeletal muscle and metabolism. In 2016, joined AstraZeneca do Brasil to act as a medical-scientific coordinator in the areas of Diabetes, Heart Failure and Chronic Kidney Disease. Currently, works as a Medical Relationship Manager at Pfizer do Brasil, focusing on Amyloidosis. (Source: Lattes Curriculum)
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Insulin resistance in skeletal muscle is a common characteristic of diabetic patients. It was recently demonstrated a strong association between ATM deficiency and oxidative stress, a favorable condition for the development of neurodegenerative, metabolic and oncogenic diseases. Under oxidative stress state, the transcription of PGC1-± is downregulated, increasing evidence that activation…
There are several situations in which insulin resistance is common, such as obesity and type 2 Diabetes mellitus. In these situations it is also observed increased free fatty acid (FA) in plasma and for this reason, it has been postulated its involvement in the establishment of resistance. However, the mechanisms involved are not completely known. Recent studies are suggestive that the sa…
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