CV Lattes
Secretaria da Saúde (São Paulo - Estado). Instituto Butantan (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduate at Faculdade de Ciências Exatas e Experimentais from Universidade Presbiteriana Mackenzie (1998) and ph.d. at Biochemistry from Universidade Federal de São Paulo (2003). Has experience in Biochemistry, focusing on Molecular Biology, acting on the following subjects: thimet, hemopressin, neurolisina, ace and neurolysin. (Source: Lattes Curriculum)
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The present project intends to develop an efficient system for expression and purification of two important therapeutics targets, metallopeptidases ECE-1 (Endotelin 1 converting enzyme; EC 3.4.24.71) and NEP (Neprilysin; EC 3.4.24.11). The expression of these recombinant enzymes will be carried through in Pichia pastoris. Also, it will be our objective to inactivate these enzymes by site-…
Accidents caused by scorpion pose a serious public health problem in Brazil. In fact, the number of accidents involving human subjects has increased in recent years. In Brazil, most of the fatalities resulting from accidents are caused by Tityus serrulatus scorpions. This is due to the frequency of their occurrence and their potential to induce severe clinical manifestations. Despite the …
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