Hugo dos Santos is currently pursuing his PhD thesis in the Chemistry Institute of University of Campinas (UNICAMP). He has experience in Chemistry, focusing on Organic Synthesis and Catalysis. (Source: Lattes Curriculum)
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This PhD project aims to explore the potentiality of the Morita-Baylis-Hillman adducts as efficient building blocks for the synthesis of commercially important biologically active substances. The project is divided in two subprojects. In the first one, we intend to increase the scope for the use of a bifunctional base, recently used in our research group, as catalyst for the Morita-Baylis…
This undergraduate research project aims at carrying out kinetic resolution of carbonates derived from Morita-Baylis-Hillman, using an enantioselective allylic hydroxylation. The chiral adducts will be employed as starting material for the synthesis of chiral 1,8-dihydronaphthyridines and dihydroquinolines (AU)
This undergraduate research project has as main target the preparation of a chiral synthetic intermediate to be used in the total synthesis of pirrolizidinic alkaloids, from a chiral Morita-Baylis-Hillman adduct. The latter will be prepared from a natural aminoacid. (AU)
| 3 / 3 | Completed scholarships in Brazil |
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SILVA, THIAGO S.; RODRIGUES, JR., MANOEL T.; SANTOS, HUGO; ZEOLY, LUCAS A.; ALMEIDA, WANDA P.; BARCELOS, ROSIMEIRE C.; GOMES, RALPH C.; FERNANDES, FABIO S.; COELHO, FERNANDO. Recent advances in indoline synthesis. Tetrahedron, v. 75, n. 14, p. 2063-2097, APR 5 2019. (18/02611-0, 13/07600-3, 15/09205-0, 16/23005-6)
RODRIGUES JR, MANOEL T.; SANTOS, HUGO; ZEOLY, LUCAS A.; SIMONI, DEBORAH A.; MOYANO, ALBERT; COELHO, FERNANDO. Preparation of tetrahydro-1H-xanthen-1-one and chromen-1-one derivatives via a Morita-Baylis-Hillman/oxa-Michael/elimination cascade. ARKIVOC, n. 2, p. 77+, 2020. (13/07600-3, 15/09205-0, 18/02611-0, 17/02364-0)
GOMES, RALPH C.; BARCELOS, ROSIMEIRE C.; RODRIGUES, JR., MANOEL T.; SANTOS, HUGO; COELHO, FERNANDO. Intermolecular Stetter Reactions on Morita-Baylis-Hillman Adducts: an Approach to Highly Functionalized 1,4-Dicarbonyl Compounds. CHEMISTRYSELECT, v. 2, n. 3, p. 926-930, JAN 2017. (13/10449-5, 15/09205-0, 13/07600-3)
FERNANDES, FABIO S.; SANTOS, HUGO; LIMA, SAMIA R.; CONTI, CAROLINE; RODRIGUES JR, MANOEL T.; ZEOLY, LUCAS A.; FERREIRA, LEONARDO L. G.; KROGH, RENATA; ANDRICOPULO, ADRIANO D.; COELHO, FERNANDO. Discovery of highly potent and selective antiparasitic new oxadiazole and hydroxy-oxindole small molecule hybrids. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, v. 201, SEP 1 2020. (18/02611-0, 13/07600-3, 16/23005-6, 15/09205-0)
RAICH, LLUIS; SANTOS, HUGO; GOMES, JULIANA C.; RODRIGUES, JR., MANOEL T.; GALAVERNA, RENAN; EBERLIN, MARCOS N.; COELHO, FERNANDO; ROVIRA, CARME; MOYANO, ALBERT. Can an Alcohol Act As an Acid/Base Catalyst in Water Solution? An Experimental and Theoretical Study of Imidazole Catalysis of the Aqueous Morita-Baylis--Hillman Reaction. ACS CATALYSIS, v. 8, n. 3, p. 1703-1714, MAR 2018. (13/10449-5, 15/09205-0, 13/07600-3)
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