Claudio Chrysostomo Werneck

• Abstract

  Fibrillin-1 is an important microfibril network component. Microfibrils are present in elastic fiber responsible for resilience and elastic properties from structures like lungs, skin and large vessels. Mutations in Fibrillin-1 gene are associated with Marfan's Syndrome. Marfan's Syndrome patients shown many different clinical manifestations in lungs, cardiovascular tract and eyes tissues…

  Evaluation on elastic fiber synthesis in cell culture obtained from fibrillin-1 defficient mice: Losartan's effect studies, AP.R

• Abstract

  Fibrillin-1 is an important microfibril network component. Microfibrils are present in elastic fiber responsible for resilience and elastic properties from structures like lungs, skin and large vessels. Mutations in Fibrillin-1 gene are associated with Marfan's Syndrome. Marfan's Syndrome patients shown many different clinical manifestations in lungs, cardiovascular tract and eyes tissues…

  Evaluation of fibrillin-1's role in arterial thrombogenesis, AP.R

• Abstract

  Project: Evaluation of Fibrillin-1's role in arterial thrombogenesis.State University of Campinas- UNICAMP.AbstractFibrillin-1 is an important microfibril network component. Microfibrils are present in elastic fiber responsible for resilience and elastic properties from structures like lungs, skin and large vessels. Mutations in Fibrillin-1 gene are associated with Marfan's Syndrome. Marf…

  Evaluation of Fibrillin-1's role in arterial thrombogenesis., BP.IC

• Abstract

  MAGP1 is a microfibril component. Many in vitro studies have shown MAGP1 interacts with fibrillin -1 and -2, tropoelastin and others. Although any pathology has been related to MAGP1 deficiency or gene mutations, zebra fish studies have shown that MAGP1 expression is critical for vascular development where changes are associated with decreased integrin/extracellular matrix interaction. Da…

  Evaluation MAGP-1's function in neointimal formation., BP.MS

• Abstract

  Mutations in the gene of fibrillin-1, present in the elastic fiber, are related to the Marfan syndrome, a dominant autosomic genetic disease, characterized by a disorder in the connective tissue. Carriers of this syndrome frequently exhibit anomalies in skeletal, pulmonary, cardic, ocular, and vessel structures, among others. The majority of its symptoms are likely related to a hyper-acti…

  Evaluation of fibrillina-1 role in arterial thrombogenesis, BP.DR

(Only some records are available in English at this moment)