CV Lattes
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Universidade de São Paulo (USP). Instituto de Física de São Carlos (IFSC) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Graduate at Engenharia de Materiais from Universidade Federal de São Carlos (1997), master's at Material and Metallurgical Engineering from Universidade Federal de São Carlos (1999) and ph.d. at Ciência e Engenharia de Materiais from Universidade de São Paulo (2003). Has experience in Nanomedicine and Nanotoxicology, especially in the design, synthesis and application of nanoparticles in cancer diagnosis and treatment. Dr Zucolotto has published more than 220 peer reviewed papers and holds more than 30 patents in nanomedicine areas.javascript:void(0) (Source: Lattes Curriculum)
| Articles published in Pesquisa FAPESP Magazine about the researcher: |
| Inicio, caída, renovación, recomienzo |
| Start, fall down, get up, start over |
| Biosensores en medicina |
| Accurate particles |
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| News published in Agência FAPESP Newsletter about the researcher |
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The applications of nanotechnology in medicine have expanded our ability to develop multifunctional structures that combine diagnostic and therapeutic functions in a single nanostructured complex. These materials have shown interest for several applications, mainly in the diagnosis and treatment of infectious diseases and cancer. This project aims at developing new nanostructured material…
The present proposal establishes the continuity and expansion of the activities of the National Institute of Science and Technology in Stem Cells and Cell Therapy, one of the National Institutes of Science and Technology created by CNPq/FAPESP in 2008. In that opportunity, we proposed the development of an extensive program of basic and clinical research to understand, isolate, culture an…
Recent advances in nanoscience and nanotechnology have expanded our ability to develop multifunctional nanostructures that combine therapeutic and diagnostic functions into a single nanostructured complex. These materials, called "teranostics", have been interesting for many applications, especially in the early diagnosis and treatment of diseases, including cancer. The versatility of the…
(Only some records are available in English at this moment)
Glioblastoma multiforme (GBM) is the most prevalent primary malignant brain tumor, characterized by poor prognosis and low long-term survival rates. Despite advancements in multimodal therapies and a deeper understanding of its biology, treatment remains challenging due to the presence of glioma stem cells, which confer resistance to chemotherapy and radiotherapy, as well as the blood-bra…
Soybeans (Glycine max), one of the main global agricultural commodities, are severely affected by Asian soybean rust (ASR), caused by the biotrophic fungus Phakopsora pachyrhizi. This pathogen can reduce productivity by up to 90%, leading to substantial economic losses and an increased dependence on chemical fungicides. However, the effectiveness of these fungicides has diminished due to …
Traditional fertilizers, although essential for plant development, can result in the degradation of soil quality, water and air pollution, and cause resistance in insects considered pests for crops. In light of this, innovative solutions emerge, such as microbial biological control agents (MBCAs), which act as elicitors, capable of interacting with plants inducing resistance or stimulatin…
(Only some records are available in English at this moment)
Glioblastoma multiforme (GBM) is a malignant brain tumor with a poor long-term prognosis. Despite the aggressive standard of care that includes surgical resection, radiotherapy, and chemotherapy, its highly invasive nature and the high impermeability of the blood-brain barrier (BBB) make it difficult to determine tumor extent and deliver therapeutic agents to the brain appropriately. In a…
Neuroblastoma (NB) is an extracranial tumor with high incidence in pediatric patients, and its biological complexity results in low survival rates. Despite advances in conventional treatments (surgery, radiotherapy, and chemotherapy), it has been observed that over the last three decades, few successes have been achieved in terms of patient survival rates, which are still considered very …
Cancer is among the leading causes of mortality worldwide, with colorectal cancer being the second most lethal, presenting a high incidence globally, surpassed only by lung cancer. In Brazil, it is estimated that the number of cases will increase in the next three years, with women being the most affected. 5-Fluorouracil (5-FU) is one of the most commonly used chemotherapy drugs for color…
(Only some records are available in English at this moment)
Delivering therapeutic agents to the brain remains a major challenge due to the blood-brain barrier (BBB), a selective interface that restricts molecular transport into the central nervous system (CNS). Nanotechnology offers promising solutions, particularly through biomimetic carriers that enhance brain targeting and immune evasion. This project aims to evaluate the biological interactio…
Glioblastoma multiforme (GBM) is the most advanced and aggressive type of primary brain tumor, and the development of effective therapies remains a pharmaceutical challenge and a critical unmet medical need. One of the main obstacles in GBM therapy is the blood-brain barrier (BBB), a highly selective barrier that prevents many drugs, especially large therapeutic agents, from reaching the …
The excessive use of antibiotics in agriculture has led to the emergence of antibiotic- resistant bacteria, as observed in the case of Pseudomonas fluorescens. This species has gained significance in public health due to its resistance to adverse conditions, biofilm formation, and its capacity to produce thermostable proteolytic and lipolytic enzymes. The development of new therapeutic st…
Cancer is responsible for six million deaths annually. Despite the widespread use of chemotherapy to control neoplastic growth, numerous challenges such as lack of specificity, adverse effects, and resistance due to tumor heterogeneity are encountered. Doxorubicin (DOX) is a widely used anticancer drug to treat various cancer types. However, they are associated with limitations such as no…
The use of nanocarriers for drug delivery has attracted significant attention for its potential to overcome limitations associated with conventional treatment methods, especially in cancer therapy. Among various nanoparticles (NPs) investigated for this purpose, calcium phosphate (CaP) NPs have emerged as highly promising nanocarriers due to their outstanding biocompatibility, biodegradab…
(Only some records are available in English at this moment)
| 2 / 2 | Ongoing grants |
| 8 / 7 | Completed research grants |
| 11 / 11 | Ongoing scholarships in Brazil |
| 54 / 47 | Completed scholarships in Brazil |
| 2 / 2 | Ongoing scholarships abroad |
| 12 / 12 | Completed scholarships abroad |
| 89 / 81 | All research grants and scholarships |
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