CV Lattes
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Universidade Estadual Paulista (UNESP). Campus de Araraquara. Faculdade de Ciências Farmacêuticas (FCFAR) (Institutional affiliation from the last research proposal) Birthplace: Brazil
bachelor's at Farmácia from Universidade Metodista de Piracicaba (2002), master's at Pharmacy from Universidade Estadual Paulista Júlio de Mesquita Filho (2004) and doctorate at Pharmacy from Universidade Estadual Paulista Júlio de Mesquita Filho (2007). Has experience in Pharmacy, focusing on Pharmacotechnie, acting on the following subjects: estágio supervisionado, sistemas líquido-cristalinos, assessoria científica, cafeína and estabilidade físico-química. (Source: Lattes Curriculum)
| Articles published in Pesquisa para Inovação FAPESP about the researcher: |
| Scientists use chitosan to develop more stable antioxidant microparticles for cosmetics |
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The analytical power and versatility of current laser-based flow cytometry systems have strengthened relatively new fields of research, such as nanotechnology. Flow cytometry has proven to be a very powerful technique for investigating cellular events related to cancer, such as oxidative stress, autophagy, changes in the cell cycle and apoptosis. In the cellular uptake process, it can be …
Glioblastoma multiforme (GBM) is the most aggressive and prevalent variation of glioma. The first choice treatment is temozolamide (TMZ), an alkylating agent administered orally or intravenously. However, the drug has some limitations, such as the difficulty in crossing the blood-brain barrier (BBB) and the cellular efflux mechanism resistance. As a consequence, the survival rate of pati…
Candida albicans is the most prevalent yeast in vulvovaginal candidiasis (VVC) episodes. Currently, the available therapy for this infection involves the administration of drugs, however, several resistance cases has been observed. Due to these factors, the search for new sources of antifungal molecules, among them, the natural products derivatives is in expansion. The hypericin (HIP) is …
Candida albicans is the most prevalent yeast in vulvovaginal candidiasis (VVC) episodes. Currently, the available therapy for this infection involves the administration of drugs, however, several resistance cases has been observed. Due to these factors, the search for new sources of antifungal molecules, among them, the natural products derivatives is in expansion. The hypericin (HIP) is …
Current anticancer therapies often demonstrate reduced safety and efficacy, so the development of new therapeutic approaches to cancer has been the goal of much research. In this context, activation of the host immune system against tumor antigens has received special attention as it represents a significantly safer and more effective alternative than chemotherapy and other conventional c…
(Only some records are available in English at this moment)
Glioblastoma multiforme is considered the most aggressive type of brain tumor and presents limitations in conventional therapies, due to the difficulty of drugs in crossing the blood-brain barrier (BBB), requiring high doses to obtain the therapeutic effect, and thus contributing to the occurrence of numerous adverse effects. Temozolomide is the gold standard chemotherapy drug for treatme…
Alzheimer's disease (AD) is characterized by a progressive cognitive decline and represents a significant concern for public health worldwide, predominating as the leading cause of dementia among the elderly and encompassing 60 to 80% of all dementia cases worldwide. Current pharmacological therapies act only on symptoms, leaving gaps in the effective treatment of the condition, which mot…
Glioblastoma multiforme (GBM) is the most common and aggressive malignant tumor affecting the Central Nervous System (CNS), with high mortality and low survival rates. Temozolomide (TMZ) is the chemotherapy of choice for GBM treatment, an alkylating agent administered orally. However, the drug has limitations such as short plasma half-life, lack of cellular specificity, toxicity to both t…
(Only some records are available in English at this moment)
Colorectal cancer (CRC) ranks third in terms of global cancer-related deaths, being one of the five most diagnosed types of cancer worldwide. The therapeutic management of this condition must be carried out under careful analysis since currently, available therapeutic measures can negatively impact the patient's quality of life. 5-fluorouracil (5-FLU) is the drug of choice for the treatme…
The treatment of colorectal cancer (CC), although effective, is associated with numerous limitations, such as the lack of specificity/selectivity of drugs, leading to systemic side effects. Curcumin (CUR) has been the subject of several researches for the treatment of different types of cancers due to its antitumor activity; however, it has low aqueous solubility, low stability, and probl…
Helicobacter pylori colonizes the gastric epithelium and is often associated with infections such as gastric disorders, gastritis, ulcers, mucosa-associated lymphoid tissue (MALT lymphoma) and even gastric adenocarcinomas. The difficulties faced in treating infections caused by this bacterium drive the search for new alternatives, such as natural products with antimicrobial activity, such…
(Only some records are available in English at this moment)
Neurodegenerative diseases, such as Alzheimer's, Parkinson's, and Huntington's,share the common feature of pathological protein aggregation that becomes toxic to braintissue, leading to cell death. While in Alzheimer's, beta-amyloid (¿A) and Tau proteinsaggregate in insoluble amyloid plaques and neurofibrillary tangles, in Parkinson'sdisease (PD) alpha-synuclein (aSyn), a presynaptic neur…
Arboviruses are diseases transmitted by hematophagous arthropods, especially the Aedes genus. As neglected diseases have difficulty accessing specific treatment, the use of repellents is described as the best form of prevention. Formulations with synthetic active repellents are widespread on the market. However, they can create risks for the user, as well as damage the environment. In add…
Colorectal cancer (CRC) ranks third in global cancer-related deaths and is one of the five most commonly diagnosed types of cancer worldwide. 5-fluorouracil (5-FLU) is the drug of choice for the treatment of CRC; however, it presents unstable absorption in the gastrointestinal tract (GIT), problems related to its high hydrophilicity, short plasma half-life, and variation in its pharmacoki…
(Only some records are available in English at this moment)
Postbiotics are substances released or produced by the metabolic activity of microorganisms, which exert a beneficial effect on the host, directly or indirectly, and may include many different constituents, in which short-chain fatty acids (SCFA) stand out. due to their excellent anti-inflammatory and immunomodulatory properties in combating prevalent intestinal diseases, however, SCFAs h…
Ulcerative colitis (UC) and Crohn's disease (CD) are inflammatory bowel diseases (IBD) characterized by chronic inflammation without cure in the gastrointestinal tract (GIT), mainly in the colon. Treatment focuses on controlling the disease, preventing recurrence, and improving the patient's quality of life. Mesalazine (MLZ) is the drug of first choice for the treatment of IBD but has lim…
Glioblastoma multiforme (GBM) is the most frequent and most aggressive Central Nervous System (CNS) cancer. Temozolomide (TMZ), the first-line drug for the treatment of GBM, has clinical efficacy, but treatment with this drug is associated with the development of resistance in more advanced stages of the disease, in addition to the fact that TMZ has physical-chemical limitations that hind…
(Only some records are available in English at this moment)
| 3 / 3 | Ongoing grants |
| 10 / 8 | Completed research grants |
| 9 / 9 | Ongoing scholarships in Brazil |
| 50 / 50 | Completed scholarships in Brazil |
| 5 / 5 | Ongoing scholarships abroad |
| 28 / 28 | Completed scholarships abroad |
| 105 / 103 | All research grants and scholarships |
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