CV Lattes
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Universidade de São Paulo (USP). Escola de Artes, Ciências e Humanidades (EACH) (Institutional affiliation from the last research proposal) Birthplace: Cuba
Bachelor's degree in Chemical Engineering from University of Matanzas "Camilo Cienfuegos"/Cuba (1997), Master of Science degree in Pharmaceutical Chemistry from University of Havana/Cuba (2006) and Ph.D. in Applications of Nuclear Technologies from University of Sao Paulo/Brazil (2011). Post-doctoral fellow at Chemical Engineering Department-University of São Paulo/Brazil (2011-2013). Assistant Professor at Department of Biological Sciences-Sao Paulo State University (Campus-Assis)/Brazil (2013-2015). Professor in Graduate Program of Biosciences-Sao Paulo State University (2014-2017). Visiting Professor at Federal University of ABC (UFABC) (2016-2017). Postdoctoral Associate in Center for Biomedical Innovation (CBI) at Massachusetts Institute of Technology (MIT) (2017-2018). Habilitation in Bioprocess Engineering (2024). Currently, he is working as an Associate Professor in Bioprocess Engineering at Center of Arts, Sciences and Humanities from University of Sao Paulo (EACH-USP). Until 2008, he was researcher at Center for Chemical Engineering and Researches, at Center of Molecular Immunology, at Center for Genetic Engineering and Biotechnology and Visiting Professor at Institute of Pharmacy and Foods of University of Havana; all of them are Cuban institutions. He has experiences in Biochemical Process, Bioprocess and Aquifer Monitoring, Industrial Pharmacy, Radiopharmacy, Chemical Reactors and Chemometrics. (Source: Lattes Curriculum)
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Vaccine production technology named virus-like particles (VLP) has been establishing itself in the commercial applications of these pharmaceutical bioproducts. These nanostructures comprising viral proteins are safer than traditional vaccines (attenuated and inactivated virus) and more immunogenic than subunits. Among the VLP production platforms, the baculovirus/insect cell (B/IC) system…
Rabies virus (RABV), belonging to the Lyssavirus genus, is the causative agent of rabies, a zoonotic disease with a fatality rate close to 100%, with more than 74,000 victims annually. Transmitted mainly by dogs, rabies affects the central nervous system and is fatal in humans, highlighting the need for prophylaxis. Despite the efficacy of existing vaccines, their production is expensive …
As objectives from the Immunization Agenda 2030 (IA2030), the World Health Organization has stated the necessity to amplify access to vaccines to all countries to balance its distribution and raise vaccination coverage, as these represent the main prophylaxis method for most infectious diseases. Vaccines against viral diseases caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SAR…
The production of viral vaccines, one of the most relevant classes of products within pharmaceutical biotechnology due to their positive impact on quality of life and the reduction of costs for national health systems, can be done through multiple platforms, such as through virus-like particles (VLP). Through this alternative, a protective immune response is generated with low doses. Cons…
(Only some records are available in English at this moment)
The Zika Virus (ZIKV) has become a global threat by spreading and manifesting a disease that varies from asymptomatic to severe manifestations. There is no specific treatment for the pathology caused by this virus and, despite the urgency, the development of a vaccine faces challenges. In this sense, Virus-Like Particles (VLPs) have emerged as an innovative approach, as they are structure…
In the development of biopharmaceuticals, it is essential to optimize the cost and quality of the final product. To this end, it is essential to monitor and control critical parameters of the procedure from the bench scale to facilitate scaling up to the industrial plant while maintaining the quality of the bioproduct. Techniques for monitoring the process, such as spectroscopy, are used …
In the current scenario of biopharmaceutical industries, it is essential to monitor bioprocesses, allowing the characterization and optimization of stages and the control of critical parameters throughout the process to ensure product quality, high yield, and productivity. Through multiparameter analytical techniques, it is possible to monitor biochemical variables with quick, financially…
(Only some records are available in English at this moment)
| 1 / 1 | Ongoing grants |
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| 5 / 5 | Ongoing scholarships in Brazil |
| 12 / 11 | Completed scholarships in Brazil |
| 20 / 19 | All research grants and scholarships |
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