CV Lattes
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Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. Escola Paulista de Medicina (EPM) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduate at Licenciatura Em Química from Universidade Federal do Rio Grande do Sul (2001), master's at Chemistry from Universidade Federal do Rio Grande do Sul (2004) and ph.d. at Chemistry from Universidade Federal do Rio Grande do Sul (2008). Has experience in Chemistry, focusing on Physical Chemistry, acting on the following subjects: espalhamento de luz, nanopartículas, carreadores de fármacos, fosfatidilcolina and suspensão coloidal. (Source: Lattes Curriculum)
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The functionalized cubosome consists of a lipid nanoparticle with a defined crystalline structure and a biopolymer coating that provides pH-responsiveness and a consequent change in the crystalline structure, including phase transitions. These characteristics contribute to possible applications of this material as a drug delivery system, mainly for the oral administration route. This prop…
The smart cubosome is a hybrid nanoparticle composed of a liquid-crystalline cubosome core and a biopolymer-based shell. The cubosome core, featuring an Im3m symmetry, is formed using the monoolein lipid, while the shell is created from complex coacervates of chitosan-N-arginine and alginate polysaccharides. This shell imparts pH-responsive properties to the nanoparticle, making it highly…
Research into bicontinuous cubic phase nanostructured materials is expanding, especially as delivery systems for applications of bioactive agents in medicine. The functionalization of nanocarrier cubosomes by conjugation with pH-responsive biopolymers offers promising possibilities for oral drug delivery, driving a new generation of therapies especially against cancer. In this project we …
(Only some records are available in English at this moment)
The efficient oral administration of drugs and bioactive substances, especially anti-cancer agents, represents a scientific and technological challenge due to the resulting low bioavailability. To overcome this challenge, nano-structured and functionalized materials such as systems for carrying and controlled release represent technology of high interest. In this proposal, we will develop…
(Only some records are available in English at this moment)
This project aims to develop a strategy of innovative aspects in the treatment of endoparasites in ornamental fish, producing and evaluating the application of nanoparticles with specific molecular characteristics and biological interaction. These composite nanoparticles of chitosan-N-arginine and alginate will be developed as a carrier system of antihelminthic drugs, ivermectin and meben…
This project intends to develop a composite material of antiparasitic properties for application in biological environment, as well as to explore innovative scientific and technical methods producing relevant scientific data from these. Composite particles on the nanoscale will be produced with the chitosan polysaccharide associated with the polysaccharide alginate, both polymers of natur…
With this project, we intend to enhance undergraduate research and support studies of photoprotection of biological membrane models, which is one of the topics of research in progress under the coordination of Prof. Rosangela Itri and developed in the post doctoral project of Omar Mertins. Through microscopic monitoring and sometimes with use of mechanical and electrical techniques couple…
(Only some records are available in English at this moment)
Cubosomes represent a nano structured colloidal system with high capacity for encapsulation of drugs and bioactive agents and promising application as a system of controlled release and release thereof. The internal structure of the cubosomes, which consists of three-dimensional networks of lipid bilayers with crystalline topologies, can be redefined by the incorporation of macromolecules…
With this project of post-doctorate abroad (BEPE) we intend to enhance and develop the study of photo protection of model membranes, in follow-up to the project being implemented by post-doctorate Omar Mertins. The work done so far has shown an effective protection of lipid membranes with the use of gallic acid in the dispersion medium of giant vesicles. Quantitative studies allowed us to…
| 4 / 4 | Ongoing grants |
| 4 / 4 | Completed research grants |
| 4 / 4 | Completed scholarships in Brazil |
| 2 / 2 | Completed scholarships abroad |
| 14 / 14 | All research grants and scholarships |
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