Abstract
Colon cancer is the third most frequent in men and the second in women, with increasing rates of morbidity and mortality in the world. Some studies suggest the involvement of genetic variants in the predisposition to colon cancer, such as chromosome locus 9q22.2-31.2 that has a linkage with familial colon cancer, where the Ki-1/57 gene is in imbalance. Ki-1/57 is a nuclear and cytoplasmic…