Time to exhaustion at anaerobic threshold in swimming rats: metabolic investigation

Author(s)

Beck, W. F. ^{[1, 2]} ; De Araujo, G. G. ^[3] ; Menezes Scariot, P. P. ^[1] ; Masselli dos Reis, I. G. ^{[1, 2]} ; Gobatto, C. A. ^{[1, 2]}

Affiliation

^[1] Univ Estadual Campinas, Fac Ciencias Aplicadas, Lab Fisiol Aplicada Esporte, BR-13484350 Sao Paulo - Brazil

^[2] Univ Estadual Campinas, Fac Educ Fis, BR-13484350 Sao Paulo - Brazil

^[3] Univ Fed Alagoas, Maceio, Alagoas - Brazil

• Document type: Journal article
• Source: BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY; v. 115, n. 10, p. 617-621, 2014.
• Web of Science Citations: 1

Abstract

The purpose of this study was to determine the time to exhaustion (film) for swimming exercise at anaerobic threshold (AT) intensity in rats and to analyze metabolic consequences on serum and tissues levels. Eighteen rats were divided in control (CG) and exercised (EG) groups, being the former submitted to film. We analyzed the glycogen content of liver and ten skeletal muscles, as well as serum parameters. Parametric statistic was used with significance level at p < 0.05. The film, which was correspondent to 114.37 +/- 36.23 min, promoted significant decrease in blood glucose (42.99 %; p < 0.01) and an increase in free fatty acids (167.12 %; p < 0.01) when EG was compared to CG. We did not find differences in albumin, total protein uric acid and creatinine between groups. The proposed exercise at individualized AT intensity promoted severe glycogen depletion for all tissues (mean of 78.05 % for all muscles and 89 % for liver). With substantial control of exercise intensity, our study establishes a useful rodent model that can be further explored, contributing to the advancement on knowledge and better understanding of exhaustion mechanisms (Tab. 1, Fig. 2, Ref. 35). Text in PDF www.elis.sk. (AU)

• FAPESP's process: 10/13377-7 - Effects of light and time of day of swimming exercise until exhaustion at lactate minimum intensity on biochemistry and hematologic responses of rats
• Grantee: Wladimir Rafael Beck
• Support Opportunities: Scholarships in Brazil - Master
• FAPESP's process: 11/13226-1 - Ergogenic response of melatonin during the nadir and acrophase of spontaneous activity: consequences on IKK/Nf-kB via
• Grantee: Wladimir Rafael Beck
• Support Opportunities: Scholarships in Brazil - Doctorate