| Full text | |
| Author(s): |
Total Authors: 2
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| Affiliation: | [1] Univ Fed Sao Carlos, Dept Quim, BR-13565905 Sao Carlos, SP - Brazil
Total Affiliations: 1
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| Document type: | Journal article |
| Source: | JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC; v. 113, p. 90-94, MAR 2015. |
| Web of Science Citations: | 6 |
| Abstract | |
Xylaria arbuscula was collected from a ``Cypress{''} tree, Cupressus lusitanica. The whole cells of this endophytic fungus were used in screening for microbial bioreduction of aryl acids. Different p-substituted benzoic acids were evaluated. However, only p-bromobenzoic acid, p-chlorobenzoic acid and p-nitrobenzoic acid were converted to their corresponding alcohols. Aryl acid metabolism of X. arbuscula included GABA incorporation and glycosylation when the substrates were p-bromobenzoic and p-chlorobenzoic acids were also observed. The substrates p-hydroxybenzoic and p-aminobenzoic acids were not transformed. These results could suggest that electron-withdrawing groups at para orientation activate the substrate for reduction. (C) 2015 Elsevier B.V. All rights reserved. (AU) | |
| FAPESP's process: | 10/11384-6 - Biotransformation of natural and synthetic products using endophytic microorganisms, a chemical-ecologycal approach for the production of bioactive substances |
| Grantee: | Edson Rodrigues Filho |
| Support Opportunities: | Regular Research Grants |
| FAPESP's process: | 13/18603-3 - Metabolic and biosynthetic studies for the chemical and taxonomic contribution of Xylariaceae family microorganisms |
| Grantee: | Luciana da Silva Amaral |
| Support Opportunities: | Scholarships in Brazil - Doctorate |