The total synthesis of (-)-cryptocaryol A

Dias, L. C.; Kuroishi, P. K.; de Lucca, Jr., E. C.

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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

The total synthesis of (-)-cryptocaryol A

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Author(s):	Dias, L. C. ^[1] ; Kuroishi, P. K. ^[1] ; de Lucca, Jr., E. C. ^[1] Total Authors: 3
Affiliation:	^[1] Univ Estadual Campinas, Inst Quim, BR-13083970 Campinas, SP - Brazil Total Affiliations: 1
Document type:	Journal article
Source:	ORGANIC & BIOMOLECULAR CHEMISTRY; v. 13, n. 12, p. 3575-3584, 2015.
Web of Science Citations:	11
Abstract
A stereoselective total synthesis of (-)-cryptocaryol A (1) is described. Key features of the 17-step route include the use of three boron-mediated aldol reaction-reduction sequences to control all stereocenters and an Ando modification of the Horner-Wadsworth-Emmons olefination that permitted the installation of the Z double bond of the alpha-pyrone ring. (AU)

FAPESP's process:	12/02230-0 - Total synthesis of bioactive compounds: biological tests and design of new analogs
Grantee:	Luiz Carlos Dias
Support Opportunities:	Regular Research Grants


FAPESP's process:	13/07600-3 - CIBFar - Center for Innovation in Biodiversity and Drug Discovery
Grantee:	Glaucius Oliva
Support Opportunities:	Research Grants - Research, Innovation and Dissemination Centers - RIDC

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