| Full text | |
| Author(s): Show less - |
Irinyi, Laszlo
[1]
;
Serena, Carolina
[1, 2]
;
Garcia-Hermoso, Dea
[3]
;
Arabatzis, Michael
[4]
;
Desnos-Ollivier, Marie
[3]
;
Vu, Duong
[5]
;
Cardinali, Gianluigi
[6]
;
Arthur, Ian
[7]
;
Normand, Anne-Cecile
[8, 9]
;
Giraldo, Alejandra
[10]
;
Cassia da Cunha, Keith
[10]
;
Sandoval-Denis, Marcelo
[10]
;
Hendrickx, Marijke
[11]
;
Nishikaku, Angela Satie
[12]
;
de Azevedo Melo, Analy Salles
[12]
;
Merseguel, Karina Bellinghausen
[12]
;
Khan, Aziza
[1]
;
Parente Rocha, Juliana Alves
[13]
;
Sampaio, Paula
[14]
;
da Silva Briones, Marcelo Ribeiro
[15]
;
Carmona e Ferreira, Renata
[15]
;
de Medeiros Muniz, Mauro
[16]
;
Castanon-Olivares, Laura Rosio
[17]
;
Estrada-Barcenas, Daniel
[17]
;
Cassagne, Carole
[8, 9]
;
Mary, Charles
[8, 9]
;
Duan, Shu Yao
[1]
;
Kong, Fanrong
[18]
;
Sun, Annie Ying
[19, 20]
;
Zeng, Xianyu
[18]
;
Zhao, Zuotao
[18]
;
Gantois, Nausicaa
[21]
;
Botterel, Francoise
[22]
;
Robbertse, Barbara
[23]
;
Schoch, Conrad
[23]
;
Gams, Walter
[5]
;
Ellis, David
[24]
;
Halliday, Catriona
[18]
;
Chen, Sharon
[1, 18]
;
Sorrell, Tania C.
[1]
;
Piarroux, Renaud
[8, 9]
;
Colombo, Arnaldo L.
[12]
;
Pais, Celia
[14]
;
de Hoog, Sybren
[5]
;
Zancope-Oliveira, Rosely Maria
[16]
;
Taylor, Maria Lucia
[17]
;
Toriello, Conchita
[17]
;
de Almeida Soares, Celia Maria
[13]
;
Delhaes, Laurence
[21]
;
Stubbe, Dirk
[11]
;
Dromer, Francoise
[3]
;
Ranque, Stephane
[8, 9]
;
Guarro, Josep
[10]
;
Cano-Lira, Jose F.
[10]
;
Robert, Vincent
[5]
;
Velegraki, Aristea
[4]
;
Meyer, Wieland
[1]
Total Authors: 57
|
| Affiliation: Show less - | [1] Univ Sydney, Marie Bashir Inst Infect Dis & Bioscur, Ctr Infect Dis & Microbiol, Westmead Hosp, Mol Mycol Res Lab, Sydney Med Sch, Westmead Millenn, Sydney, NSW 2006 - Australia
[2] Univ Rovira & Virgili, Inst Invest Sanitaria Rovira & Virgili IISPV, Hosp Joan XXIII, Unitat Recerca, E-43007 Tarragona - Spain
[3] CNRS, Inst Pasteur, Natl Reference Ctr Invas Mycoses & Antifungals, Mol Mycol Unit, URA3012, Paris - France
[4] Univ Athens, Univ Athens Hellen Collect Pathogen Fungi UOA HCP, Sch Med, Mycol Res Lab, Dept Microbiol, Athens 11528 - Greece
[5] CBS KNAW, Fungal Biodivers Ctr, Utrecht - Netherlands
[6] Univ Perugia, Dept Pharmaceut Sci, I-06100 Perugia - Italy
[7] QEII Med Ctr, PathWest Lab Med WA, Dept Microbiol & Infect Dis, Mycol Lab, Nedlands, WA - Australia
[8] CHU Timone Adultes, APHM, Parasitol Mycol, Marseille - France
[9] Aix Marseille Univ, UMR MD3 IP TPT, Marseille - France
[10] Univ Rovira & Virgili, IISPV, Fac Med & Ciencies Salut, Unitat Microbiol, E-43201 Reus - Spain
[11] Sci Inst Publ Hlth, Biomed Fungi & Yeasts Collect, BCCM IHEM, Brussels - Belgium
[12] Univ Fed Sao Paulo, Escola Paulista Med, Lab Especial Micol, Sao Paulo - Brazil
[13] Univ Fed Goias, Inst Ciencias Biol, Lab Biol Mol, Goiania, Go - Brazil
[14] Univ Minho, Sch Sci, Dept Biol, Ctr Mol & Environm Biol CBMA, Braga - Portugal
[15] Univ Fed Sao Paulo, Escola Paulista Med, Lab Genom & Biocomplexidade Evolut, Sao Paulo - Brazil
[16] Fundacao Oswald Cruz Fiocruz, Inst Pesquisa Clin Evandro Chagas IPEC, Rio De Janeiro - Brazil
[17] Univ Nacl Autonoma Mexico, Dept Microbiol & Parasitol, Fac Med, Unidad Micol, Ciudad Mexico - Mexico
[18] Westmead Hosp, Ctr Infect Dis & Microbiol, Westmead, NSW 2145 - Australia
[19] Univ Adelaide, Sch Paediat & Reprod Hlth, Adelaide, SA - Australia
[20] Univ Adelaide, Robinson Inst, Adelaide, SA - Australia
[21] Univ Lille 2, Inst Pasteur Lille, CHU Lille, BDEEP EA4547, CIIL, Lille - France
[22] CHU Henri Mondor, AP HP, Unite Parasitol Mycol, Dynamyc Team, F-94010 Creteil - France
[23] NIH, Natl Ctr Biotechnol Informat, Natl Lib Med, Bethesda, MD 20892 - USA
[24] Univ Adelaide, SA Pathol, Mycol & Infect Dis, Adelaide, SA - Australia
Total Affiliations: 24
|
| Document type: | Review article |
| Source: | Medical Mycology; v. 53, n. 4, p. 313-337, MAY 2015. |
| Web of Science Citations: | 100 |
| Abstract | |
Human and animal fungal pathogens are a growing threat worldwide leading to emerging infections and creating new risks for established ones. There is a growing need for a rapid and accurate identification of pathogens to enable early diagnosis and targeted antifungal therapy. Morphological and biochemical identification methods are time-consuming and require trained experts. Alternatively, molecular methods, such as DNA barcoding, a powerful and easy tool for rapid monophasic identification, offer a practical approach for species identification and less demanding in terms of taxonomical expertise. However, its wide-spread use is still limited by a lack of quality-controlled reference databases and the evolving recognition and definition of new fungal species/complexes. An international consortium of medical mycology laboratories was formed aiming to establish a quality controlled ITS database under the umbrella of the ISHAM working group on ``DNA barcoding of human and animal pathogenic fungi.{''} A new database, containing 2800 ITS sequences representing 421 fungal species, providing the medical community with a freely accessible tool at http://www.isham.org and http://its.mycologylab.org/ to rapidly and reliably identify most agents of mycoses, was established. The generated sequences included in the new database were used to evaluate the variation and overall utility of the ITS region for the identification of pathogenic fungi at intra-and interspecies level. The average intraspecies variation ranged from 0 to 2.25%. This highlighted selected pathogenic fungal species, such as the dermatophytes and emerging yeast, for which additional molecular methods/genetic markers are required for their reliable identification from clinical and veterinary specimens. (AU) | |
| FAPESP's process: | 07/08575-1 - Hematogenic candidiasis: a multidisciplinary approach for the improvement of diagnostic tools and caracterization of biomarkers related to its prognosis |
| Grantee: | Arnaldo Lopes Colombo |
| Support Opportunities: | Research Projects - Thematic Grants |