| Full text | |
| Author(s): |
Castello-Simoes, Viviane
[1]
;
Minatel, Vinicius
[1]
;
Karsten, Marlus
[1, 2]
;
Simoes, Rodrigo Polaquini
[1]
;
Perseguini, Natalia Maria
[1]
;
Milan, Juliana Cristina
[1]
;
Arena, Ross
[3, 4]
;
Tomazi Neves, Laura Maria
[1]
;
Borghi-Silva, Audrey
[1]
;
Catai, Aparecida Maria
[1]
Total Authors: 10
|
| Affiliation: | [1] Univ Fed Sao Carlos, Lab Fisioterapia Cardiovasc, Nucleo Pesquisa Exercicio Fis, BR-13565905 Sao Carlos, SP - Brazil
[2] Univ Fed Ciencias Saude Porto Alegre, Dept Fisioterapia, Porto Alegre, RS - Brazil
[3] Univ Illinois, Fac Ciencias Aplicadas Saude, Dept Fisioterapia, Chicago, IL - USA
[4] Univ Illinois, Fac Ciencias Aplicadas Saude, Lab Fisiologia Integrat, Chicago, IL - USA
Total Affiliations: 4
|
| Document type: | Journal article |
| Source: | Arquivos Brasileiros de Cardiologia; v. 104, n. 6, p. 476-485, JUN 2015. |
| Web of Science Citations: | 2 |
| Abstract | |
Background:Circulatory power (CP) and ventilatory power (VP) are indices that have been used for the clinical evaluation of patients with heart failure; however, no study has evaluated these indices in patients with coronary artery disease (CAD) without heart failure.Objective:To characterize both indices in patients with CAD compared with healthy controls.Methods:Eighty-seven men [CAD group = 42 subjects and healthy control group (CG) = 45 subjects] aged 40–65 years were included. Cardiopulmonary exercise testing was performed on a treadmill and the following parameters were measured: 1) peak oxygen consumption (VO2), 2) peak heart rate (HR), 3) peak blood pressure (BP), 4) peak rate-pressure product (peak systolic HR x peak BP), 5) peak oxygen pulse (peak VO2/peak HR), 6) oxygen uptake efficiency (OUES), 7) carbon dioxide production efficiency (minute ventilation/carbon dioxide production slope), 8) CP (peak VO2 x peak systolic BP) and 9) VP (peak systolic BP/carbon dioxide production efficiency).Results:The CAD group had significantly lower values for peak VO2 (p < 0.001), peak HR (p < 0.001), peak systolic BP (p < 0.001), peak rate-pressure product (p < 0.001), peak oxygen pulse (p = 0.008), OUES (p < 0.001), CP (p < 0.001), and VP (p < 0.001) and significantly higher values for peak diastolic BP (p = 0.004) and carbon dioxide production efficiency (p < 0.001) compared with CG. Stepwise regression analysis showed that CP was influenced by group (R2 = 0.44, p < 0.001) and VP was influenced by both group and number of vessels with stenosis after treatment (interaction effects: R2 = 0.46, p < 0.001).Conclusion:The indices CP and VP were lower in men with CAD than healthy controls. (AU) | |
| FAPESP's process: | 10/52070-4 - New approaches for evaluation of cardiovascular oscillations changes with aging |
| Grantee: | Aparecida Maria Catai |
| Support Opportunities: | Regular Research Grants |