Psychotropic Drug Use in Sao Paulo, Brazil - An Epidemiological Survey

Author(s)

Quintana, Maria Ines ^[1] ; Andreoli, Sergio Baxter ^{[2, 1]} ; Peluffo, Marcela Poctich ^[2] ; Ribeiro, Wagner Silva ^[1] ; Feijo, Marcelo M. ^[1] ; Bressan, Rodrigo Affonseca ^[1] ; Coutinho, Evandro S. F. ^[3] ; Mari, Jair de Jesus ^[1]

Affiliation

^[1] Univ Fed Sao Paulo, Escola Paulista Med, Dept Psychiat, Sao Paulo - Brazil

^[2] Univ Catolica Santos, Santos - Brazil

^[3] Fundacao Oswaldo Cruz, Escola Nacl Saude Publ, Rio De Janeiro - Brazil

• Document type: Journal article
• Source: PLoS One; v. 10, n. 8 AUG 7 2015.
• Web of Science Citations: 6

Abstract

Objective To estimate the prevalence of one month psychotropic drug use in Sao Paulo, Brazil, and to assess the gap treatment between the presence of mental disorders and psychotropic drug users. Method A probabilistic sample of non-institutionalized individuals from the general population of Sao Paulo (n = 2336; turnout: 84.5%) who were 15 years or older were interviewed by a trained research staff, applying the Composite International Diagnostic Interview 2.1 (CIDI WHO) (depression, anxiety-phobia, OCD\textbackslash{}PTSD, alcoholism sections), and an inventory investigating psychotropic drug use during the 12-month and one-month periods immediately preceding the interview. Logistic models were fitted to investigate associations between psychotropic drug use as well as socio-demographic and clinical variables. Results The one month prevalence of psychotropic drug use in Sao Paulo was 5.89%, the most commonly used drugs were antidepressants (3.15%) and tranquilizers (2.67%). A higher consumption of psychotropic drugs (overall, antidepressants and tranquilizers) was observed among women (OR:2.42), older individuals (OR:1.04), individuals with higher levels of formal education (1.06), and individuals with a family (OR:2.29) or personal history of mental illness (OR:3.27). The main psychotropic drug prescribers were psychiatrists (41%), followed by general practitioners (30%); 60% of psychotropic drugs were obtained through a government-run dispensing program. Most individuals who obtained a positive diagnosis on the CIDI 2.1 during the previous month were not using psychotropic medication (85%). Among individuals with a diagnosis of moderate to severe depression, 67.5% were not on any pharmacological treatment. Conclusion There is a change in the type of psychotropic more often used in Sao Paulo, from benzodiazepines to antidepressants, this event is observed in different cultures. The prevalence of use is similar to other developing countries. Most of the patients presenting a psychiatric illness in the month prior to testing were not receiving any sort of psychiatric medication. This may be explained by a failure to identify cases in primary care, which could be improved (and access to treatment could be facilitated) if professionals received more specialized training in managing cases with mental health problems. (AU)

• FAPESP's process: 04/15039-0 - Post-traumatic stress disorder: epidemiology, physiopathology and treatment
• Grantee: Jair de Jesus Mari
• Support Opportunities: Research Projects - Thematic Grants