Hepatitis E virus infection in Brazil: results of laboratory-based surveillance from 1998 to 2013

Author(s)

Passos-Castilho, Ana Maria ^[1] ; de Sena, Anne ^{[1, 2]} ; Reinaldo, Monica Renata ^{[1, 2]} ; Hernandes Granato, Celso Francisco ^{[1, 2]}

Affiliation

^[1] Univ Fed Sao Paulo, Dept Med, Sao Paulo - Brazil

^[2] Grp Fleury SA, Fleury Med & Saude, Sao Paulo - Brazil

• Document type: Journal article
• Source: Revista da Sociedade Brasileira de Medicina Tropical; v. 48, n. 4, p. 468-470, JUL-AUG 2015.
• Web of Science Citations: 13

Abstract

INTRODUCTION:Data on hepatitis E virus (HEV) in Brazil are limited. We analyzed 15 years of HEV surveillance data in a major clinical laboratory in São Paulo, Brazil.METHODS:The seroprevalence of HEV of 2,271 patients subjected to anti-HEV tests from 1998 to 2013 were analyzed.RESULTS:HEV seroprevalence was 2.1%, and the anti-HEV IgM positivity rate was 4.9%. Six hepatitis E patients were identified.CONCLUSIONS:HEV seroprevalence and detection rates appear to have increased in recent years. Hepatitis E should be investigated further and included in the differential diagnosis of hepatitis in Brazil. (AU)

• FAPESP's process: 12/22925-3 - Hepatitis e virus infection in immunocompromised patients: detection, viral load determination and molecular characterization
• Grantee: Celso Francisco Hernandes Granato
• Support Opportunities: Regular Research Grants
• FAPESP's process: 13/03701-0 - Identification of lipidomic markers with diagnostic potential in hepatocellular carcinoma
• Grantee: Ana Maria Passos
• Support Opportunities: Scholarships in Brazil - Doctorate