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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Light-emitting diode therapy in exercise-trained mice increases muscle performance, cytochrome c oxidase activity, ATP and cell proliferation

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Ferraresi, Cleber [1, 2, 3, 4] ; Parizotto, Nivaldo Antonio [2, 3] ; Pires de Sousa, Marcelo Victor [1, 5] ; Kaippert, Beatriz [1, 6] ; Huang, Ying-Ying [1, 7] ; Koiso, Tomoharu [1, 8] ; Bagnato, Vanderlei Salvador [4] ; Hamblin, Michael R. [1, 7, 9]
Total Authors: 8
[1] Massachusetts Gen Hosp, Wellman Ctr Photomed, Boston, MA 02114 - USA
[2] Univ Fed Sao Carlos, Dept Phys Therapy, Lab Electrothermophototherapy, BR-13560 Sao Carlos, SP - Brazil
[3] Univ Fed Sao Carlos, Postgrad Program Biotechnol, BR-13560 Sao Carlos, SP - Brazil
[4] Univ Sao Paulo, Phys Inst Sao Carlos, Opt Grp, Sao Carlos, SP - Brazil
[5] Univ Sao Paulo, Inst Phys, Lab Radiat Dosimetry & Med Phys, BR-05508 Sao Paulo - Brazil
[6] Univ Fed Rio de Janeiro, BR-21941 Rio De Janeiro - Brazil
[7] Harvard Univ, Sch Med, Dept Dermatol, Boston, MA 02115 - USA
[8] Tohoku Univ, Grad Sch Biomed Engn, Sendai, Miyagi 980 - Japan
[9] Harvard MIT Div Hlth Sci & Technol, Cambridge, MA - USA
Total Affiliations: 9
Document type: Journal article
Source: Journal of Biophotonics; v. 8, n. 9, p. 740-754, SEP 2015.
Web of Science Citations: 21

Light-emitting diode therapy (LEDT) applied over the leg, gluteus and lower-back muscles of mice using a LED cluster (630nm and 850nm, 80mW/cm(2), 7.2J/cm(2)) increased muscle performance (repetitive climbing of a ladder carrying a water-filled tube attached to the tail), ATP and mitochondrial metabolism; oxidative stress and proliferative myocyte markers in mice subjected to acute and progressive strength training. Six bi-daily training sessions LEDT-After and LEDT-Before-After regimens more than doubled muscle performance and increased ATP more than tenfold. The effectiveness of LEDT on improving muscle performance and recovery suggest applicability for high performance sports and in training programs. {[}GRAPHICS] Positioning of the mice and light-emitting diode therapy (LEDT) applied on mouse legs, gluteus and lower-back muscles without contact. (AU)

FAPESP's process: 10/07194-7 - Use of low-level laser and light-emitting diode therapy to increase muscle performance: from in vitro and experimental studies to clinical applications
Grantee:Cleber Ferraresi
Support type: Scholarships in Brazil - Doctorate
FAPESP's process: 12/05919-0 - Effects of low level laser therapy on modulation of the transcriptome, immunohistochemistry of muscle tissue and physical performance of young men undergoing physical strength training
Grantee:Cleber Ferraresi
Support type: Scholarships abroad - Research Internship - Doctorate