| Full text | |
| Author(s): |
Badial, Peres R.
[1]
;
Cisneros-Alvarez, Luis Emiliano
[2]
;
Brandao, Claudia Valeria S.
[3]
;
Ranzani, Jose Joaquim T.
[3]
;
Tomaz, Mayana A. R. V.
[3]
;
Machado, Vania M.
[2]
;
Borges, Alexandre S.
[1]
Total Authors: 7
|
| Affiliation: | [1] UNESP Univ Estadual Paulista, Dept Vet Clin Sci, Botucatu, SP - Brazil
[2] UNESP Univ Estadual Paulista, Dept Anim Reprod & Vet Radiol, Botucatu, SP - Brazil
[3] UNESP Univ Estadual Paulista, Dept Vet Surg & Anesthesiol, Botucatu, SP - Brazil
Total Affiliations: 3
|
| Document type: | Journal article |
| Source: | VETERINARY OPHTHALMOLOGY; v. 18, n. 5, p. 385-392, SEP 2015. |
| Web of Science Citations: | 8 |
| Abstract | |
ObjectivesThe aim of this study was to compare ocular dimensions, corneal curvature, and corneal thickness between horses affected with hereditary equine regional dermal asthenia (HERDA) and unaffected horses. AnimalsFive HERDA-affected quarter horses and five healthy control quarter horses were used. MethodsSchirmer's tear test, tonometry, and corneal diameter measurements were performed in both eyes of all horses prior to ophthalmologic examinations. Ultrasonic pachymetry was performed to measure the central, temporal, nasal, dorsal, and ventral corneal thicknesses in all horses. B-mode ultrasound scanning was performed on both eyes of each horse to determine the dimensions of the ocular structures and to calculate the corneal curvature. ResultsEach corneal region examined in this study was thinner in the affected group compared with the healthy control group. However, significant differences in corneal thickness were only observed for the central and dorsal regions. HERDA-affected horses exhibited significant increases in corneal curvature and corneal diameter compared with unaffected animals. The ophthalmologic examinations revealed mild corneal opacity in one eye of one affected horse and in both eyes of three affected horses. No significant between-group differences were observed for Schirmer's tear test, intraocular pressure, or ocular dimensions. ConclusionsHereditary equine regional dermal asthenia-affected horses exhibit decreased corneal thickness in several regions of the cornea, increased corneal curvature, increased corneal diameter, and mild corneal opacity. Additional research is required to determine whether the increased corneal curvature significantly impacts the visual accuracy of horses with HERDA. (AU) | |
| FAPESP's process: | 10/08774-7 - Hereditary Equine Regional Dermal Asthenia clinical and molecular study |
| Grantee: | Peres Ramos Badial |
| Support Opportunities: | Scholarships in Brazil - Doctorate |
| FAPESP's process: | 09/17764-8 - Hereditary Equine Regional Dermal Asthenia clinical and molecular study |
| Grantee: | Alexandre Secorun Borges |
| Support Opportunities: | Regular Research Grants |