Ultrasound-assisted extraction method for the simultaneous determination of emerging contaminants in freshwater sediments

Author(s)

Ribeiro de Sousa, Diana Nara ^[1] ; Grosseli, Guilherme Martins ^[1] ; Mozeto, Antonio Aparecido ^[1] ; Carneiro, Renato Lajarim ^[2] ; Fadini, Pedro Sergio ^[1]

Affiliation

^[1] Univ Fed Sao Carlos UFSCar, Dept Quim, Lab Biogeoquim Ambiental, BR-13565905 Sao Carlos, SP - Brazil

^[2] Univ Fed Sao Carlos UFSCar, Dept Quim, Grp Quimiometria Aplicada, BR-13565905 Sao Carlos, SP - Brazil

• Document type: Journal article
• Source: JOURNAL OF SEPARATION SCIENCE; v. 38, n. 19, p. 3454-3460, OCT 2015.
• Web of Science Citations: 8

Abstract

Sediments are the fate of several emerging organic contaminants, such as pharmaceuticals, personal care products and hormones, and therefore an important subject in environmental monitoring studies. In the present work, a simple and sensitive method was developed, validated and applied for the simultaneous extraction of atenolol, caffeine, carbamazepine, diclofenac, ibuprofen, naproxen, propranolol, triclosan, estrone, 17-beta-estradiol and 17-alpha-ethinylestradiol using ultrasound-assisted extraction from freshwater sediment samples followed by solid-phase extraction clean-up and liquid chromatography with tandem mass spectrometry detection. The solvent type and extraction pH were evaluated to obtain the highest recoveries of the compounds. The best method shows absolute recoveries between 54.0 and 94.4% at 50 ng/g concentration. The method exhibits good precision with relative standard deviation ranging from 1.0-16%. The detection and quantification limits ranged from 0.006-0.067 and 0.016-0.336 ng/g, respectively. The developed method was successfully applied to freshwater sediment samples collected from different sites in Jundiai River basin of Sao Paulo State, Brazil. The compounds atenolol, caffeine, propranolol and triclosan were detected in all the sampling sites with concentrations of 13.8, 41.0, 28.5 and 176 ng/g, respectively. (AU)

• FAPESP's process: 10/01731-0 - Occurrence and distribution of emerging contaminants at watershed of Jundiaí River - São Paulo
• Grantee: Pedro Sergio Fadini
• Support Opportunities: Regular Research Grants