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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

The Morita-Baylis-Hillman Reaction: Advances and Contributions from Brazilian Chemistry

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Author(s):
Santos, Marilia S. [1] ; Coelho, Fernando [1] ; Lima-Junior, Claudio G. [2] ; Vasconcellos, Mario L. A. A. [2]
Total Authors: 4
Affiliation:
[1] Univ Estadual Campinas, Dept Organ Chem, Inst Chem, Campinas, SP - Brazil
[2] Univ Fed Paraiba, Dept Chem, BR-58059900 Joao Pessoa, Paraiba - Brazil
Total Affiliations: 2
Document type: Journal article
Source: CURRENT ORGANIC SYNTHESIS; v. 12, n. 6, p. 830-852, 2015.
Web of Science Citations: 12
Abstract

The Morita-Baylis-Hillman reaction is an organocatalyzed chemical transformation that allows access to small poly-functionalized molecules and has considerable synthetic potential and promising biological profiles. In this review, we report the efforts made by Brazilian research groups in recent years on the development of Morita-Baylis-Hillman chemistry. The review covers these contributions, with a focus on mechanistic studies, improvement of the experimental conditions, and the use of Morita-Baylis-Hillman adducts as building blocks for the synthesis of heterocycles, natural products and drugs. (AU)

FAPESP's process: 13/10449-5 - Morita-Baylis-Hillman adducts as efficient building blocks for the synthesis of molecules of biological interest
Grantee:Fernando Antonio Santos Coelho
Support Opportunities: Regular Research Grants
FAPESP's process: 12/08048-0 - Morita-Baylis-Hillman in medicinal chemistry: design, synthesis and biological evaluation of potential antifungal agents
Grantee:Marília Simão dos Santos
Support Opportunities: Scholarships in Brazil - Doctorate