| Full text | |
| Author(s): |
da Silva, Carolina Feher
[1]
;
Silva Morgero, Kelly Cristina
[2]
;
Mota, Amanda Manzini
[2]
;
Pimentel Piemonte, Maria Elisa
[3]
;
Chrysostomo Baldo, Marcus Vinicius
[2]
Total Authors: 5
|
| Affiliation: | [1] Univ Sao Paulo, Dept Gen Phys, Inst Phys, BR-05508090 Sao Paulo, SP - Brazil
[2] Univ Sao Paulo, Inst Biomed Sci, Dept Physiol & Biophys, BR-05508000 Sao Paulo - Brazil
[3] Univ Sao Paulo, Fac Med, Dept Phys Therapy Phonoaudiol & Occupat Therapy, BR-05508000 Sao Paulo - Brazil
Total Affiliations: 3
|
| Document type: | Journal article |
| Source: | Neuropsychologia; v. 78, p. 1-9, NOV 2015. |
| Web of Science Citations: | 4 |
| Abstract | |
Objective: Our study evaluates how aging and Parkinson's disease (PD) alter temporal order judgment (TOJ). Method: Two TOJ experiments were performed with young participants, healthy elderly participants, and PD patients. Two white squares were presented on opposite sides of a screen and participants responded which appeared first. In Experiment 1, it was assessed how accurately each group could judge temporal order at intervals from 0 ms to 167 ms. Detectability, the capacity of detecting which stimulus appeared first, was measured. In Experiment 2, participants were asked to orient their attention to the hemifield indicated by a cue. The PSS ({''}point of subjective simultaneity{''}), where the participant was equally likely to respond that either stimulus appeared first, was measured. Results: In Experiment 1, PD patients had smaller detectability than healthy elderly (p < 0.05) and young participants (p < 0.001), and healthy elderly participants had smaller detectability than young participants (p < 0.001). In Experiment 2, PSS was 29 ms for young participants, 121 ms for healthy elderly participants, and 283 ms for PD patients; differences were statistically significant for comparisons between PD patients and healthy elderly participants (p < 0.001), PD patients and young participants (p < 0.001), and healthy elderly and young participants (p < 0.04). Conclusions: TOJ is impaired by aging and PD. Our results suggest that dopamine loss increases latency and variability in visual decision making due to a lower signal-to-noise ratio in the visual pathways. (C) 2015 Elsevier Ltd. All rights reserved. (AU) | |
| FAPESP's process: | 03/11139-8 - Temporal dynamics of visual perception and its sensory, attentional and behavioral modulation |
| Grantee: | Marcus Vinícius Chrysóstomo Baldo |
| Support Opportunities: | Regular Research Grants |
| FAPESP's process: | 13/10694-0 - The role of reward and the basal ganglia in decision making |
| Grantee: | Carolina Feher da Silva |
| Support Opportunities: | Scholarships in Brazil - Post-Doctoral |