| Full text | |
| Author(s): |
De Souza, Michele N.
[1]
;
Xavier, Fernando E. B.
[2]
;
Secaf, Marie
[2]
;
Troncon, Luiz E. A.
[2]
;
de Oliveira, Ricardo B.
[2]
;
Moraes, Eder R.
[1]
Total Authors: 6
|
| Affiliation: | [1] Univ Sao Paulo, Dept Phys, Fac Philosophy Sci & Language Ribeirao Preto, BR-14040901 Sao Paulo - Brazil
[2] Univ Sao Paulo, Dept Med, Fac Med Ribeirao Preto, BR-14040901 Sao Paulo - Brazil
Total Affiliations: 2
|
| Document type: | Journal article |
| Source: | NUCLEAR MEDICINE COMMUNICATIONS; v. 37, n. 1, p. 87-91, JAN 2016. |
| Web of Science Citations: | 0 |
| Abstract | |
PurposeThis paper presents a novel method to compute oesophageal transit velocity in a direct and automatized manner by the registration of scintigraphy images.MethodsA total of 36 images from nine healthy volunteers were processed. Four dynamic image series per volunteer were acquired after a minimum 8h fast. Each acquisition was made following the ingestion of 5ml saline labelled with about 26MBq (700 mu Ci) technetium-99m phytate in a single swallow. Between the acquisitions, another two swallows of 5ml saline were performed to clear the oesophagus. The composite acquired files were made of 240 frames of anterior and posterior views. Each frame is the accumulate count for 250ms.At the end of acquisitions, the images were corrected for radioactive decay, the geometric mean was computed between the anterior and posterior views and the registration of a set of subsequent images was performed. Utilizing the improved Demons technique, we obtained from the deformation field the regional resultant velocity, which is directly related to the oesophagus transit velocity.ResultsThe mean regional resulting velocities decreases progressively from the proximal to the distal oesophageal portions and, at the proximal portion, is virtually identical to the primary peristaltic pump typical velocity. Comparison between this parameter and time-activity' curves reveals consistency in velocities obtained using both methods, for the proximal portion.ConclusionApplication of the improved Demons technique, as an easy and automated method to evaluate velocities of oesophageal bolus transit, is feasible and seems to yield consistent data, particularly for the proximal oesophagus. (AU) | |
| FAPESP's process: | 11/05011-5 - Study of gastric and esophagus dynamics on cintilographic images by demons technique |
| Grantee: | Michele Noccioli de Souza |
| Support Opportunities: | Scholarships in Brazil - Master |
| FAPESP's process: | 10/07639-9 - Gastrointestinal motility: clinical investigations, physiopathology and biopharmaceutical |
| Grantee: | Ricardo Brandt de Oliveira |
| Support Opportunities: | Research Projects - Thematic Grants |