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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Vulcanization, centrifugation, water-washing, and polymeric covering processes to optimize natural rubber membranes applied to microfluidic devices

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Author(s):
Cabrera, Flavio C. [1] ; Dognani, Guilherme [1] ; Faita, Fabricio L. [2] ; dos Santos, Renivaldo J. [3] ; Agostini, Deuber L. S. [1] ; Bechtold, Ivan H. [4] ; Crespilho, Frank N. [5] ; Job, Aldo E. [1]
Total Authors: 8
Affiliation:
[1] UNESP, Fac Ciencias & Tecnol, Dept Fis Quim & Biol, BR-19060900 Presidente Prudente, SP - Brazil
[2] Univ Minho, Ctr Phys, P-4710057 Braga - Portugal
[3] Univ Estadual Paulista, Sao Paulo, SP - Brazil
[4] Univ Fed Santa Catarina, Dept Fis, BR-88040900 Florianpolis, SC - Brazil
[5] Univ Sao Paulo, Inst Quim, Sao Carlos, SP - Brazil
Total Affiliations: 5
Document type: Journal article
Source: Journal of Materials Science; v. 51, n. 6, p. 3003-3012, MAR 2016.
Web of Science Citations: 4
Abstract

Natural rubber microfluidic devices are based on the replication of microchannels and chambers through the casting of latex and combine the flexibility and transparency of the polymeric platform. Natural rubber is a proposed alternative material to prepare microfluidic devices, owing to the advantages of flexibility, eco-friendliness, and lower cost compared to other commonly used polymeric microfluidic materials. However, the challenges for the use of natural rubber are the leaching of compounds when it is in contact with fluids, the low stretching resistance, and the decreases of transparency rate in terms of the water absorption rate. To overcome these issues, we report the evaluation of the essential mechanical, optical, and structural properties of natural rubber for centrifuged and pre-vulcanized rubber membranes, as well as the polymeric coating over the membrane surfaces. We propose the centrifugation process for decreasing the leach composition of the natural rubber platform and vulcanization to improve the mechanical resistance of the polymeric membrane devices. The polymeric coating prevents the leaching of compounds from natural rubber membranes and water absorption without significant reduction in transparency or increase in the hydrophobicity of the surface. Once the centrifuging, vulcanization, and coating processes improve the rubber properties, this polymer will become an alternative flexible and low-cost material for microfluidic technology. (AU)

FAPESP's process: 11/23362-0 - NATURAL RUBBER-BASED MICROFLUIDIC DEVICE (LAB-ON-A-SHIP)
Grantee:Flávio Camargo Cabrera
Support Opportunities: Scholarships in Brazil - Doctorate
FAPESP's process: 13/04663-4 - Enzymatic bioelectrodes applied in biofuel cells: experimental and simulation
Grantee:Frank Nelson Crespilho
Support Opportunities: Regular Research Grants
FAPESP's process: 13/14262-7 - Nanostructured films from biologically-relevant materials
Grantee:Osvaldo Novais de Oliveira Junior
Support Opportunities: Research Projects - Thematic Grants