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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

alpha-MsO/TsO/Cl Ketones as Oxidized Alkyne Equivalents: Redox-Neutral Rhodium(III)-Catalyzed C-H Activation for the Synthesis of N-Heterocycles

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Yu, Da-Gang [1] ; de Azambuja, Francisco [1] ; Glorius, Frank [1]
Total Authors: 3
[1] Univ Munster, Inst Organ Chem, D-48149 Munster - Germany
Total Affiliations: 1
Document type: Journal article
Source: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION; v. 53, n. 10, p. 2754-2758, MAR 3 2014.
Web of Science Citations: 92

-Halo and pseudohalo ketones are used for the first time as C(sp(3))-based electrophiles in transition-metal-catalyzed CH activation and as oxidized alkyne equivalents in Rh-III-catalyzed redox-neutral annulations to generate diverse N-heterocycles. This transformation is efficient and scalable. Due to the mild reaction conditions, a variety of functional groups could be tolerated. (AU)

FAPESP's process: 13/14209-9 - Development of a new intermolecular asymmetric Fujiwara-Moritani reaction: a new synthetic tool to obtain biologically active moieties
Grantee:Francisco de Azambuja
Support type: Scholarships abroad - Research Internship - Doctorate