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(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

CLINICAL, HEMATOLOGICAL, AND SEMINAL ALTERATIONS AND PARASITEMIA OF MALE GOATS EXPERIMENTALLY INFECTED WITH Toxoplasma gondii

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Author(s):
Luís Fernando Santana [1] ; Roberta Cordeiro Gaspar [2] ; Gabriel Augusto Marques Rossi [3] ; Gabriel Antônio Nogueira Nascentes [4] ; Eliana Aparecida Rodrigues [5] ; Gilson Pereira de Oliveira [6] ; Alvimar José da Costa [7]
Total Authors: 7
Affiliation:
[1] Instituto Federal de Educação, Ciência e Tecnologia do Triângulo Mineiro - Brasil
[2] Universidade Estadual Paulista. Faculdade de Ciências Agrárias e Veterinárias. Departamento de Medicina Veterinária Preventiva e Reprodução Animal - Brasil
[3] Universidade Estadual Paulista. Faculdade de Ciências Agrárias e Veterinárias. Departamento de Medicina Veterinária Preventiva e Reprodução Animal - Brasil
[4] Instituto Federal de Educação, Ciência e Tecnologia do Triângulo Mineiro - Brasil
[5] Instituto Federal de Educação, Ciência e Tecnologia do Triângulo Mineiro - Brasil
[6] Universidade Estadual Paulista. Faculdade de Ciências Agrárias e Veterinárias. Centro de Pesquisas em Sanidade Animal - Brasil
[7] Universidade Estadual Paulista. Faculdade de Ciências Agrárias e Veterinárias. Centro de Pesquisas em Sanidade Animal - Brasil
Total Affiliations: 7
Document type: Journal article
Source: Ciênc. anim. bras.; v. 16, n. 3, p. 399-409, 2015-09-00.
Abstract

<title>Abstract:</title><p>Toxoplasmosis is a parasitic disease that affects reproductive performance in small ruminants. Although the <italic>Toxoplasma gondii</italic> life cycle is well understood since 1960s, several aspects related to its infection remains unclear. This study aimed to determine the effects of <italic>T. gondii</italic>experimental infection, and the influence on clinical, hematological, parasitemia and seminal parameters in male goats. Nine animals were selected and distributed in three groups: GI (n=3) – control group (placebo) orally inoculated with saline solution; GII (n=3) – subcutaneously inoculated with 1 x 106 tachyzoites of <italic>T. gondii</italic>; and GIII (n=3) – orally inoculated with 2 x 10<sup>5</sup> oocysts of <italic>T. gondii</italic>. After that, clinical exams, serological tests, hemograms, parasitemia determination and semen evaluation were performed. Reciprocal serological titers had highest values of 4096 in both groups of goats infected with <italic>T. gondii,</italic>confirming the experimental infections. However, we could not observe clinical changes (except for mild hyperthermia on the 5<sup>th</sup> DAI in one of the animals - GIII) or in hematimetric parameters. Although there were some statistically significant changes (P <0.05) on the percentages of pathology and sperm concentrations in some of the dates between the infected and control animals, these changes were not associated with toxoplasmic infection. Infection was associated with animal handling methods and environmental factors.</p> (AU)

FAPESP's process: 08/11290-1 - Studies regarding the sexual transmission of Toxoplasma gondii in goats (Capra hircus)
Grantee:Alvimar José da Costa
Support Opportunities: Regular Research Grants