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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Clinical utility of the Montgomery-Asberg Depression Rating Scale for the detection of depression among bariatric surgery candidates

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Author(s):
Duarte-Guerra, Leorides Severo [1] ; Gorenstein, Clarice [2, 1] ; Paiva-Medeiros, Paula Francinelle [1] ; Santo, Marco Aurelio [3] ; Neto, Francisco Lotufo [1] ; Wang, Yuan-Pang [1, 4]
Total Authors: 6
Affiliation:
[1] Univ Sao Paulo, Sch Med, Dept & Inst Psychiat LIM 23, Sao Paulo - Brazil
[2] Univ Sao Paulo, Inst Biomed Sci, Dept Pharmacol, Sao Paulo - Brazil
[3] Univ Sao Paulo, Sch Med, Dept Surg, Sao Paulo - Brazil
[4] Univ Sao Paulo, Hosp Clin, Fac Med, Inst & Dept Psiquiatria, Rua Dr Ovidio Pires Campos 785, BR-05403010 Sao Paulo - Brazil
Total Affiliations: 4
Document type: Journal article
Source: BMC Psychiatry; v. 16, APR 30 2016.
Web of Science Citations: 3
Abstract

Background: Clinical assessment of depression is an important part of pre-surgical assessment among individuals with morbid obesity. However, there is no agreed-upon instrument to identify mood psychopathology in this population. We examined the reliability and criterion validity of the clinician-administered Montgomery-Asberg Depression Rating Sca (MADRS) and the utility of a short version for bariatric surgery candidates. Methods: The sample was 374 patients with obesity, consecutively recruited from the waiting list of a bariatric surgery clinic of University Hospital, Brazil: women 80 %, mean BMI 47 kg/m(2), mean age 43.0 years. The 10-item MADRS was analyzed against the SCID-I. Items that showed small relevance to sample's characteristics and contribution to data variability were removed to develop the short 5-item version of scale. We calculated the sensitivity and specificity of cutoff points of both versions MADRS, and values were plotted as a receiver operating characteristic curve. Results: For the 10-item MADRS, the Cronbach's alpha coefficient was 0.93. When compared against SCID-I, the best cut-off threshold was 13/14, yielding sensitivity of 0.81 and specificity 0.85. Following items were removed: reduced appetite, reduced sleep, concentration difficulties, suicide thought and lassitude. The 5-item version showed an alpha coefficient of 0.94 and a best cut-off threshold of 10/11, yielding sensitivity of 0.81 and specificity 0.87. Similar overall ability to discriminate depression of almost 90 % was found for both 10-item and 5-item MADRS. Conclusion: The MADRS is a reliable and valid instrument to assess depressive symptoms among treatment-seeking bariatric patients. Systematic application of the abbreviated version of the MADRS can be recommended for enhancing the clinical detection of depression during perioperative period. (AU)

FAPESP's process: 12/17498-9 - Bipolar spetrun disorders in severely obese patients candidates for bariatric surgery
Grantee:Leorides Severo Duarte Guerra
Support Opportunities: Scholarships in Brazil - Master
FAPESP's process: 12/17435-7 - Bipolar spectrum disorders among obese patients seeking bariatric surgery: mental disorders and obesity
Grantee:Wang Yuan Pang
Support Opportunities: Regular Research Grants
FAPESP's process: 12/18325-0 - Depressive symptoms among obese patients candidates for bariatric surgery
Grantee:Paula Francinelle de Medeiros Paiva
Support Opportunities: Scholarships in Brazil - Scientific Initiation