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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Evaluation of antibiofilm and mechanical properties of new nanocomposites based on acrylic resins and silver vanadate nanoparticles

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Author(s):
de Castro, Denise T. [1] ; Valente, Mariana L. C. [1] ; da Silva, Claudia H. L. [1] ; Watanabe, Evandro [1] ; Siqueira, Renato L. [2] ; Schiavon, Marco A. [3] ; Alves, Oswaldo Luiz [4] ; dos Reis, Andrea C. [1]
Total Authors: 8
Affiliation:
[1] Univ Sao Paulo, Sch Dent Ribeirao Preto, Dept Dent Mat & Prosthodont, BR-14049 Ribeirao Preto, SP - Brazil
[2] Fed Univ Sao Carlos UFSCar, Postgrad Program Mat Sci & Engn PPG CEM, Sao Carlos, SP - Brazil
[3] Fed Univ Sao Joao del Rei UFSJ, GPQM Res Grp Mat Chem, Dept Nat Sci, Sao Joao Del Rei, MG - Brazil
[4] State Univ Campinas UNICAMP, Lab Solid State Chem, Campinas, SP - Brazil
Total Affiliations: 4
Document type: Journal article
Source: ARCHIVES OF ORAL BIOLOGY; v. 67, p. 46-53, JUL 2016.
Web of Science Citations: 13
Abstract

Objective: The purpose of this study was evaluate, for the first time, the impact of incorporation of nanostructured silver vanadate (beta-AgVO3) in antibiofilm and mechanical properties of dental acrylic resins (poly(methyl methacrylate), PMMA). Design: The beta-AgVO3 was synthesized and characterized by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy, and microanalysis (SEM/EDS). Resins specimens were prepared with 0-10% wt.% beta-AgVO3 and characterized by SEM, XRD and optical microscopy. The antibiofim activity of the samples against Candida albicans and Streptococcus mutans was investigated by XTT reduction test, colony-forming units (CFUs), and confocal laser scanning microscopy (CLSM). The flexural strength, hardness, and surface roughness of the samples containing beta-AgVO3 were compared with the pure PMMA matrix. Results: The incorporation of 10% beta-AgVO3 significantly reduced the metabolic activity of C. albicans and S. mutans (p < 0.05). There was a reduction in microbial load (CFU/mL) of microorganisms for the different concentrations used (p < 0.05), which was confirmed by confocal microscopy. The addition of beta-AgVO3 did not change the mechanical properties of hardness and surface roughness of the resins (p > 0.05). However, flexural strength decreased with the addition of amounts greater than 1% (p < 0.05). Conclusions: beta-AgVO3 additions in dental acrylic resin may have an impact on inhibition of biofilm of main microorganisms associated with dental prostheses. However, the viability of clinical use should be evaluated in function of changed promoted in some mechanical properties. (C) 2016 Published by Elsevier Ltd. (AU)

FAPESP's process: 12/09124-1 - Characterization and evaluation of mechanical and antimicrobial properties of experimental dental acrylic resins: incorporation with nanostructured silver vanadate
Grantee:Andréa Cândido dos Reis
Support type: Regular Research Grants
FAPESP's process: 12/09347-0 - Influence of the incorporation of nanostructured silver vanadato in antimicrobial activity, morphology and mechanical properties of acrylic resins experimental.
Grantee:Denise Tornavoi de Castro
Support type: Scholarships in Brazil - Master