Cationic Pd(II) complexes acting as topoisomerase II inhibitors: Synthesis, characterization, DNA interaction and cytotoxicity

Author(s):Show less -

Rocha, Fillipe V. ^{[1, 2]} ; Barra, Carolina V. ^[2] ; Garrido, Saulo S. ^[3] ; Manente, Francine A. ^[4] ; Carlos, Iracilda Z. ^[4] ; Ellena, Javier ^[5] ; Fuentes, Andrea S. C. ^[6] ; Gautier, Arnaud ^[7] ; Morel, Laurent ^[8] ; Mauro, Antonio E. ^[2] ; Netto, Adelino V. G. ^[2]

Affiliation

^[1] Univ Fed Sao Carlos, Dept Chem, BR-13565905 Sao Carlos, SP - Brazil

^[2] UNESP, Inst Quim, Dept Quim Geral & Inorgan, BR-14801970 Araraquara, SP - Brazil

^[3] UNESP, Inst Quim, Dept Bioquim & Tecnol Quim, BR-14801970 Araraquara, SP - Brazil

^[4] UNESP Univ Estadual Paulista, Fac Ciencias Farmaceut Araraquara, Dept Anal Clin, POB 502, BR-14801902 Araraquara, SP - Brazil

^[5] Univ Sao Paulo, Inst Fis, BR-13560970 Sao Carlos, SP - Brazil

^[6] Univ Fed Sao Carlos, Dept Genet & Evolut, Mol Biol Lab, Rodovia Washington Luis Km 235, BR-13565905 Sao Carlos, SP - Brazil

^[7] Univ Clermont Ferrand, Clermont Univ, CNRS, ICCF, UMR 6296, F-63177 Aubiere - France

^[8] Univ Clermont Ferrand, Clermont Univ, INSERM, GreD UMR CNRS 6247, U931, 24 Ave Landais, F-63177 Aubiere - France

• Document type: Journal article
• Source: Journal of Inorganic Biochemistry; v. 159, p. 165-168, JUN 2016.
• Web of Science Citations: 11

Abstract

• FAPESP's process: 13/20156-5 - Design of new thiosemicarbazones and their Cu(II) and Pd(II) complexes as topoisomerase inhibitors
• Grantee: Fillipe Vieira Rocha
• Support Opportunities: Scholarships in Brazil - Post-Doctoral