| Full text | |
| Author(s): |
Sbardella, M.
[1]
;
Perina, D. P.
[1]
;
Andrade, C.
[2]
;
Santos, C. B.
[1]
;
Cairo, P. L. G.
[3]
;
Marques, E. L. S.
[3]
;
Rezende, R. P.
[3]
;
Costa, L. B.
[2]
;
Miyada, V. S.
[1]
Total Authors: 9
|
| Affiliation: | [1] Univ Sao Paulo, Dept Zootecnia, ESALQ, BR-13418900 Piracicaba, SP - Brazil
[2] Pontificia Univ Catolica Parana PUCPR, ECAMV, BR-83010500 Sao Jose Dos Pinhais, PR - Brazil
[3] Univ Estadual Santa Cruz, Dept Ciencias Biol, BR-45662900 Ilheus, BA - Brazil
Total Affiliations: 3
|
| Document type: | Journal article |
| Source: | ANIMAL FEED SCIENCE AND TECHNOLOGY; v. 217, p. 67-75, JUL 2016. |
| Web of Science Citations: | 4 |
| Abstract | |
The purpose of this study was to evaluate the effects of dietary graded levels of hop (Humulus lupulus) beta-acids or colistin on the growth performance, nutrient and energy digestibility, diarrhea occurrence, unthrifty pigs, blood respiratory burst, organ weights, small intestine histology, and intestinal microbial diversity of weanling pigs, as well as in vitro bacterial sensitivity to hop beta-acids. Two hundred 21-d weaned castrated male and female pigs (6.2 +/- 0.33 kg initial BW) were used in a randomized complete block design experiment with 5 treatments, 8 replicates, and 5 pigs per experimental unit (pen). Pigs were fed corn soybean meal basal diets supplemented with 0 (negative control), 120, 240, or 360 mg/kg hop beta-acids, or with 40 mg/kg colistin (antimicrobial control) during a 35-d nursery feeding experiment. On d 7 and 35 of the experiment, one castrated male from each pen was slaughtered to evaluate organ weights, small intestine histology, and intestinal microbial diversity. ANOVA and orthogonal contrasts were performed to determine the dose-response of each variable to dietary hop beta-acids levels (0,120, 240, and 360 mg/kg), as well as to compare the means of antimicrobial control with the negative control and with each dietary hop beta-acids level. Increasing dietary levels of hop beta-acids improved linearly (P < 0.05) BW, ADG, G:F, and digestibility of ether extract of feed of weanling pigs. The colistin treatment improved (P < 0.03) BW, ADG, and G:F compared to the negative control but did not affect nutrient and energy digestibility. No difference in growth performance was observed between hop beta-acids (120, 240, or 360 mg/kg) and colistin. No effect on ADFI was observed. Overall, the occurrence of diarrhea was lower (P < 0.01) for colistin, negative control, and 360 mg/kg hop beta-acids than for 120 and 240 mg/kg hop beta-acids, while no unthrifty pigs were identified throughout the entire experimental period. No effect of dietary treatments on blood respiratory burst, organ weights, small intestine histology, and intestinal microbial diversity was observed. By using the standardized paper disk diffusion method, Staphylococcus aureus was (C) 2016 Elsevier B.V. All rights reserved. (AU) | |
| FAPESP's process: | 12/00949-8 - Use of beta-acids of hops (Humulus lupulus) in weanling pig diets |
| Grantee: | Valdomiro Shigueru Miyada |
| Support Opportunities: | Regular Research Grants |
| FAPESP's process: | 12/01005-3 - Use of beta-acids of hops (Humulus lupulus) in weanling pig diets |
| Grantee: | Maicon Sbardella |
| Support Opportunities: | Scholarships in Brazil - Doctorate |