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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Control of White Spot Lesions with Use of Fluoride Varnish or Chlorhexidine Gel During Orthodontic Treatment A Randomized Clinical Trial

Restrepo, M. [1] ; Bussaneli, D. G. [1] ; Jeremias, F. [1] ; Cordeiro, R. C. L. [1] ; Raveli, D. B. [1] ; Magalhaes, A. C. [2] ; Candolo, C. [3] ; Santos-Pinto, L. [1]
Total Authors: 8
[1] Univ Estadual Paulista, Araraquara Dent Sch, Dept Orthodont & Pediat Dent, Rua Humaita 1680, BR-14801903 Araraquara, SP - Brazil
[2] Univ Sao Paulo, Bauru Sch Dent, Dept Biol Sci, Baurn, SP - Brazil
[3] Univ Fed Sao Carlos, Dept Stat, Sao Carlos, SP - Brazil
Total Affiliations: 3
Document type: Journal article
Source: Journal of Clinical Pediatric Dentistry; v. 40, n. 4, p. 274-280, SUM 2016.
Web of Science Citations: 5

Objective: To compare the effectiveness of fluoride varnish and 2% chlorhexidine gel for controlling active white spot lesions (WSLs) adjacent to orthodontic brackets. Study design: Thirty-five orthodontic patients (17.2+/-2.3 years old) presenting 60 WSLs adjacent to orthodontic brackets were enrolled in this randomized, blind, 3-armed and controlled clinical trial. The patients were randomly allocated to 1 of 3 arms: (1) two applications of 5% NaF varnish- F, with one-week interval, (2) two applications of 2% chlorhexidine gel-CHX, with one-week interval and (3) usual home care-control (CO). The WSLs were scored by using a DIAGNOdent pen. An independent examiner scored the surfaces using Nyvad criteria for caries assessment. Results: A total of thirty patients presenting 51 lesions completed the study. All treatments reduced the fluorescence values during the experimental period; however, F induced faster remineralization than CHX. After 3 months, 70.58 % were inactive considering all groups. DIAGNOdent pen and Nyvad presented a significant correlation. Conclusion: After 3 months of treatment, F, CHX and CO were capable of controlling the WSLs adjacent to the orthodontic brackets. However, the treatment with F was capable of controlling the progression of the WSLs in a shorter period of time. (AU)

FAPESP's process: 11/21012-1 - In vivo and in vitro quantification of with spot lesions remineralization adjacent to orthodontic brackets
Grantee:Lourdes Aparecida Martins dos Santos-Pinto
Support type: Regular Research Grants