Sonochemistry in organocatalytic enamine-azide [3+2] cycloadditions: A rapid alternative for the synthesis of 1,2,3-triazoyl carboxamides

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Author(s):	Xavier, Daiane M. ; Goldani, Bruna S. ; Seus, Natalia ; Jacob, Raquel G. ; Barcellos, Thiago ; Paixao, Marcio W. ; Luque, Rafael ; Alves, Diego Total Authors: 8
Document type:	Journal article
Source:	ULTRASONICS SONOCHEMISTRY; v. 34, p. 107-114, JAN 2017.
Web of Science Citations:	12
Abstract
We described herein the use of sonochemistry in the organocatalytic enamine-azide {[}3+2] cycloadditions of beta-oxo-amides with a range of substituted aryl azides. These sonochemical promoted reactions were found to be amenable to a range of beta-oxo amides or aryl azides, providing an efficient access to new N-aryl-1,2,3-triazoyl carboxamides in good to excellent yields and short times of reaction. (C) 2016 Elsevier B.V. All rights reserved. (AU)

FAPESP's process:	15/17141-1 - Development and Mechanism Studies of New Synthetic Methodologies for the Synthesis of Bioactive Compounds.
Grantee:	Ricardo Samuel Schwab
Support Opportunities:	Regular Research Grants


FAPESP's process:	14/50249-8 - Green chemistry: sustainable synthetic methods employing benign solvents, safer reagents, and bio-renewable feedstock
Grantee:	Arlene Gonçalves Corrêa
Support Opportunities:	Research Grants - Research Centers in Engineering Program