Immobilization of Amano lipase from Pseudomonas fluorescens on silk fibroin spheres: an alternative protocol for the enantioselective synthesis of halohydrins

Ferreira, Irlon M.; Yoshioka, Sergio A.; Comassetode, Joao V.; Porto, Andre L. M.

Advanced search

Search - Use quotation marks to get a more specific result

Index

Field of knowledge

Start date

Betweenand

(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Immobilization of Amano lipase from Pseudomonas fluorescens on silk fibroin spheres: an alternative protocol for the enantioselective synthesis of halohydrins

Full text
Author(s):	Ferreira, Irlon M. ; Yoshioka, Sergio A. ; Comassetode, Joao V. ; Porto, Andre L. M. Total Authors: 4
Document type:	Journal article
Source:	RSC ADVANCES; v. 7, n. 21, p. 12650-12658, 2017.
Web of Science Citations:	3
Abstract
The search for a new, efficient, cheaper and sustainable matrix for lipase immobilization is a growing area in biotechnology. Amano lipase from Pseudomonas fluorescens was immobilized on silk fibroin spheres and used in the enzymatic kinetic resolution of halohydrins, to obtain optically active epoxides (up to 99% ee), important precursors in the synthesis of derivative antifungal azoles. This paper reinforces the versatility of silk fibroin as a support for heterogeneous catalysts. (AU)

Short URL