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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Bioprospecting from cultivable bacterial communities of marine sediment and invertebrates from the underexplored Ubatuba region of Brazil

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Author(s):
Tangerina, Marcelo M. P. ; Correa, Hebelin ; Haltli, Brad ; Vilegas, Wagner ; Kerr, Russell G.
Total Authors: 5
Document type: Journal article
Source: Archives of Microbiology; v. 199, n. 1, p. 155-169, JAN 2017.
Web of Science Citations: 0
Abstract

Shrimp fisheries along the Brazilian coast have significant environmental impact due to high by-catch rates (21 kg per kilogram of shrimp). Typically discarded, by-catch contains many invertebrates that may host a great variety of bacterial genera, some of which may produce bioactive natural products with biotechnological applications. Therefore, to utilize by-catch that is usually discarded we explored the biotechnological potential of culturable bacteria of two abundant by-catch invertebrate species, the snail Olivancillaria urceus and the sea star Luidia senegalensis. Sediment from the collection area was also investigated. Utilizing multiple isolation approaches, 134 isolates were obtained from the invertebrates and sediment. Small-subunit rRNA (16S) gene sequencing revealed that the isolates belonged to Proteobacteria, Firmicutes and Actinobacteria phyla and were distributed among 28 genera. Several genera known for their capacity to produce bioactive natural products (Micromonospora, Streptomyces, Serinicoccus and Verrucosispora) were retrieved from the invertebrate samples. To query the bacterial isolates for their ability to produce bioactive metabolites, all strains were fermented and fermentation extracts profiled by UP LC-HRMS and tested for antimicrobial activity. Four strains exhibited antimicrobial activity against methicillin-resistant Staphylococcus aureus (MRSA) and Staphylococcus warneri. (AU)

FAPESP's process: 11/23159-0 - By-Catch: A Chemical Universe to be Explored
Grantee:Marcelo Marucci Pereira Tangerina
Support Opportunities: Scholarships in Brazil - Doctorate
FAPESP's process: 12/19419-9 - By catch fauna: a chemical universe to be investigated
Grantee:Wagner Vilegas
Support Opportunities: BIOTA-FAPESP Program - Regular Research Grants