Cerebral Hemodynamic Effects of Cheyne-Stokes Respiration in a Patient with Stroke

Author(s)

Nogueira, R. C. ; Panerai, R. B. ; Teixeira, M. J. ; Robinson, T. G. ; Bor-Seng-Shu, E.

• Document type: Journal article
• Source: JOURNAL OF STROKE & CEREBROVASCULAR DISEASES; v. 26, n. 5, p. E80-E82, MAY 2017.
• Web of Science Citations: 0

Abstract

Introduction: Cheyne-Stokes respiration (CSR) and central sleep apnea (CSA) are common in patients with heart failure and/or stroke. We aim to describe the cerebrovascular effects of CSR during the acute phase of stroke in a heart failure patient. Case Report: A 74-year-old male with previous dilated cardiomyopathy had sudden onset of right hemiparesis and aphasia. A transcranial Doppler was performed with continuous measurement of blood pressure (BP) (Finometer) and end-tidal CO2 (nasal capnography). Offline analysis of hemodynamic data disclosed relatively large periodic oscillations of both cerebral blood flow velocity and BP related to the CSR breathing pattern. Derivate variables from the cerebrovascular resistance were calculated (critical closing pressure and resistance-area product), demonstrating that there may be a myogenic impairment of cerebral blood flow (CBF) control in the affected hemisphere of this subgroup of patient. Conclusion: There is an impairment of CBF regulation in the affected hemisphere of the patient with ischemic stroke and CSR, highlighting the role of cerebral hemodynamic monitoring in this scenario. (AU)

• FAPESP's process: 13/25953-0 - Cerebral autoregulation in the acute and subacute phase of ischemic stroke patients submitted to thrombolysis
• Grantee: Ricardo de Carvalho Nogueira
• Support Opportunities: Regular Research Grants