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(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Cyclo-(trp-phe) diketopiperazines from the endophytic fungus Aspergillus versicolor isolated from Piper aduncum

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Author(s):
Juliana R. Gubiani [1] ; Helder L. Teles [2] ; Geraldo H. Silva [3] ; Maria Cláudia M. Young [4] ; José O. Pereira [5] ; Vanderlan S. Bolzani [6] ; Angela R. Araujo [7]
Total Authors: 7
Affiliation:
[1] Universidade Estadual Paulista. Instituto de Química. Departamento de Química Orgânica - Brasil
[2] Universidade Federal do Mato Grosso. Departamento de Ciências Biológicas - Brasil
[3] Universidade Federal de Viçosa. Instituto de Ciências Exatas e Tecnológicas - Brasil
[4] Instituto de Botânica. Núcleo de Pesquisa em Fisiologia e Bioquímica - Brasil
[5] Universidade do Amazonas. Faculdade de Ciências Agrárias - Brasil
[6] Universidade Estadual Paulista. Instituto de Química. Departamento de Química Orgânica - Brasil
[7] Universidade Estadual Paulista. Instituto de Química. Departamento de Química Orgânica - Brasil
Total Affiliations: 7
Document type: Journal article
Source: Química Nova; v. 40, n. 2, p. 138-142, 2017-02-00.
Abstract

Six known compounds, three peptide derivatives: cyclo-(tryptophyl-phenylalanyl) (2), diketopiperazine dimer WIN 64821 (3) and 3-hydroxy-15H-tryptophenaline (4), one adenine derivative: 2-hydroxy-6-N-isopentenyl-adenine (5), one phtalide derivative: 4-methoxyphtalide (1) and one benzoic acid derivative: 3-hydroxy-4-(1-hydroxy-1,5-dimethyl-hexyl) benzoic acid (6), were isolated from the ethyl acetate extract of the endophytic fungus Aspergillus versicolor associated with the Piper aduncum plant. Their structures were determined on the basis of detailed interpretation of 1 D and 2D NMR spectra and in comparison with works reported in the literature. This paper, in effect, deals with the first report of these compounds in A. versicolor. (AU)

FAPESP's process: 03/02176-7 - Conservation and sustainable use of the diversity from Cerrado and Atlantic Forest: chemical diversity and prospecting for potential drugs - phase II
Grantee:Vanderlan da Silva Bolzani
Support Opportunities: BIOTA-FAPESP Program - Thematic Grants
FAPESP's process: 13/07600-3 - CIBFar - Center for Innovation in Biodiversity and Drug Discovery
Grantee:Glaucius Oliva
Support Opportunities: Research Grants - Research, Innovation and Dissemination Centers - RIDC