| Full text | |
| Author(s): |
Total Authors: 2
|
| Affiliation: | [1] University of São Paulo. School of Medicine. Radiology Department - Brasil
[2] University of São Paulo. Radiology Department - Brasil
Total Affiliations: 2
|
| Document type: | Journal article |
| Source: | Arquivos de Neuro-Psiquiatria; v. 69, n. 1, p. 130-138, 2011-02-00. |
| Abstract | |
Malformations of cortical development (MCD) result from disruptions in the complex process of the human brain cortex formation and are highly associated to severe epilepsy, neurodevelopmental delay and motor dysfunction. Nowadays, magnetic resonance imaging (MRI) is the cornerstone of the work-up of patients with epilepsy and modern advanced imaging techniques have improved not only our ability to detect and characterize cortical malformations, but also in identifying associated functional abnormalities that are far beyond the structural visualized lesions. Herein, we address the most currently used classifications of MCD and make a concise review of the embryological process of cortical development. Our main goal is to summarize recent advances and new trends in diagnostic imaging techniques concerning MCD. Thereafter, follows a brief discussion of specific disorders and their radiological features. (AU) | |
| FAPESP's process: | 05/56464-9 - Neuroscience Imaging Center at University of São Paulo Medical School |
| Grantee: | Giovanni Guido Cerri |
| Support Opportunities: | Inter-institutional Cooperation in Support of Brain Research (CINAPCE) - Thematic Grants |