| Full text | |
| Author(s): Show less - |
Ghogare, Ashwini A.
;
Debaz, Ciro J.
;
Oliveira, Marilene Silva
;
Abramova, Inna
;
Mohapatra, Prabhu P.
;
Kwon, Kitae
;
Greer, Edyta M.
;
Prado, Fernanda Manso
;
Valerio, Hellen Paula
;
Di Mascio, Paolo
;
Greer, Alexander
Total Authors: 11
|
| Document type: | Journal article |
| Source: | Journal of Physical Chemistry A; v. 121, n. 32, p. 5954-5966, AUG 17 2017. |
| Web of Science Citations: | 3 |
| Abstract | |
A nitrosamine photooxidation reaction is shown to generate a peroxy intermediate by experimental physical-organic methods. The irradiation of phenyl and methyl-substituted nitrosamines in the presence of isotopically labeled 18-oxygen revealed that an O atom was trapped from a peroxy intermediate to trimethylphosphite or triphenylphosphine, or by nitrosamine itself, forming two moles of nitramine. The unstable peroxy intermediate can be trapped at low temperature in postphotolyzed solution in the dark. Chemiluminescence was also observed upon thermal decomposition of the peroxy intermediate, that is, when a postphotolysis low-temperature solution is brought up to room temperature. A DFT study provides tentative information for cyclic nitrogen peroxide species on the reaction surface. (AU) | |
| FAPESP's process: | 11/10048-5 - Mapping adducts generated by endogenous and exogenous aldehydes: use as biomarkers of redox stress |
| Grantee: | Marisa Helena Gennari de Medeiros |
| Support Opportunities: | Research Projects - Thematic Grants |
| FAPESP's process: | 10/50891-0 - Ácido docosahexaenóico e colesterol: caracterização e detecção de produtos de oxidação, modificação de proteínas e implicações na esclerose lateral amiotrófica |
| Grantee: | Sayuri Miyamoto |
| Support Opportunities: | Regular Research Grants |
| FAPESP's process: | 13/07937-8 - Redoxome - Redox Processes in Biomedicine |
| Grantee: | Ohara Augusto |
| Support Opportunities: | Research Grants - Research, Innovation and Dissemination Centers - RIDC |
| FAPESP's process: | 12/12663-1 - Singlet molecular oxygen and peroxides in chemical biology |
| Grantee: | Paolo Di Mascio |
| Support Opportunities: | Research Projects - Thematic Grants |