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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

In vitro production of bovine embryos: cumulus/granulosa cell gene expression patterns point to early atresia as beneficial for oocyte competence

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Author(s):
Mazzoni, Gianluca ; Razza, Eduardo ; Pedersen, Hanne S. ; Secher, Jan ; Kadarmideen, Haja N. ; Callesen, Henrik ; Stroebech, Lotte ; Freude, Kristine ; Hyttel, Poul
Total Authors: 9
Document type: Journal article
Source: ANIMAL REPRODUCTION; v. 14, n. 3, p. 482-489, JUL-SEP 2017.
Web of Science Citations: 1
Abstract

In vitro production (IW) of bovine embryos has become widespread technology implemented in cattle breeding and production. Here, we review novel data on cumulus/granulosa cell gene expression, as determined by RNAseq on cellular material from pooled follicular fluids at the single animal level, and relate these finding to previous data on oocyte developmental competence and ultrastructure. The cumulus/granulosa cell gene expression patterns indicate that early follicular atresia is associated with increased blastocyst yield and this hypothesis is supported by previous data on oocyte competence and ultrastructure. (AU)

FAPESP's process: 12/50533-2 - GIFT: genomic improvement of fertilization traits in Danish and Brazilian cattle
Grantee:Marcelo Fábio Gouveia Nogueira
Support Opportunities: Research Projects - Thematic Grants