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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Concordance of Beta-papillomavirus across anogenital and oral anatomic sites of men: The HIM Study

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Nunes, Emily M. ; Lopez, Rossana V. M. ; Sudenga, Staci L. ; Gheit, Tarik ; Tommasino, Massimo ; Baggio, Maria L. ; Ferreira, Silvaneide ; Galan, Lenice ; Silva, Roberto C. ; Lazcano-Ponce, Eduardo ; Giuliano, Anna R. ; Villa, Luisa L. ; Sichero, Laura ; Grp, HIM Study
Total Authors: 14
Document type: Journal article
Source: VIROLOGY; v. 510, p. 55-59, OCT 2017.
Web of Science Citations: 7
Abstract

We evaluated the concordance between beta-HPVs detected in external genital skin, anal canal, and oral cavity specimens collected simultaneously from 717 men that were participating in the multinational HIM Study. Viral genotyping was performed using the Luminex technology. Species- and type-specific concordance was measured using kappa statistics for agreement. Overall, concordance of P-HPVs across sites was low and mainly observed among paired genital/anal canal samples. When grouped by species, solely beta-4 HPVs showed moderate concordance in genital/anal pairs (k = 0.457), which could be attributed to the substantial concordance of HPV-92 in men from Brazil and Mexico (k > 0.610). beta-HPV type concordance was higher in Mexico, where HPV-19 was consistently concordant in all anatomic site combinations. Our analysis indicates that type-specific concordance across sites is limited to few viral types; however, these infections seem to occur more often than would be expected by chance, suggesting that although rare, there is agreement among sites. (AU)

FAPESP's process: 08/57889-1 - Institute of Science and Technology to study Diseases Associated with Papillomavirus
Grantee:Luisa Lina Villa
Support type: Research Projects - Thematic Grants
FAPESP's process: 13/20470-1 - Prevalence and diversity of Beta-papillomavirus in anogenital and oral samples of males from the HIM study
Grantee:Emily Montosa Nunes
Support type: Scholarships in Brazil - Master
FAPESP's process: 15/12557-5 - Prevalence and risk factors associated to Beta-papillomavirus detection in anogenital and oral samples of males from the HIM study
Grantee:Emily Montosa Nunes
Support type: Scholarships abroad - Research Internship - Master's degree
FAPESP's process: 13/01440-4 - Prevalence and diversity of Beta-papillomavirus in anogenital and oral samples of males from the him study
Grantee:Laura Cristina Sichero Vettorazzo
Support type: Regular Research Grants