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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Bacterial endotoxin adhesion to different types of orthodontic adhesives

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Author(s):
Romualdo, Priscilla Coutinho ; Guerra, Thais Rodrigues ; Romano, Fabio Lourenco ; Bezerra da Silva, Raquel Assed ; Brandao, Izaira Tincani ; Silva, Celio Lopes ; Bezerra da Silva, Lea Assed ; Nelson-Filho, Paulo
Total Authors: 8
Document type: Journal article
Source: Journal of Applied Oral Science; v. 25, n. 4, p. 436-441, JUL-AUG 2017.
Web of Science Citations: 0
Abstract

Abstract Bacterial endotoxin (LPS) adhesion to orthodontic brackets is a known contributing factor to inflammation of the adjacent gingival tissues. Objective The aim of this study was to assess whether LPS adheres to orthodontic adhesive systems, comparing two commercial brands. Material and Methods Forty specimens were fabricated from Transbond XT and Light Bond composite and bonding agent components (n=10/component), then contaminated by immersion in a bacterial endotoxin solution. Contaminated and non-contaminated acrylic resin samples were used as positive and negative control groups, respectively. LPS quantification was performed by the Limulus Amebocyte Lysate QCL-1000™ test. Data obtained were scored and subjected to the Chi-square test using a significance level of 5%. Results There was endotoxin adhesion to all materials (p<0.05). No statistically significant difference was found between composites/bonding agents and acrylic resin (p>0.05). There was no significant difference (p>0.05) among commercial brands. Affinity of endotoxin was significantly greater for the bonding agents (p=0.0025). Conclusions LPS adhered to both orthodontic adhesive systems. Regardless of the brand, the endotoxin had higher affinity for the bonding agents than for the composites. There is no previous study assessing the affinity of LPS for orthodontic adhesive systems. This study revealed that LPS adheres to orthodontic adhesive systems. Therefore, additional care is recommended to orthodontic applications of these materials. (AU)

FAPESP's process: 13/26611-6 - Quantification of bacterial endotoxin in different types of orthodontic adhesive systems
Grantee:Thais Rodrigues Guerra
Support Opportunities: Scholarships in Brazil - Scientific Initiation