| Full text | |
| Author(s): |
Fernandes Oliveira, Maria Regina
[1, 2]
;
Leandro, Roseli
[3, 4]
;
Decimoni, Tassia Cristina
[3]
;
Rozman, Luciana Martins
[3]
;
Dutilh Novaes, Hillegonda Maria
[3, 1]
;
De Soarez, Patricia Coelho
[3, 1]
Total Authors: 6
|
| Affiliation: | [1] Inst Avaliacao Tecnol Saude IATS CNPq, Porto Alegre, RS - Brazil
[2] Univ Brasilia, Fac Med, Campus Univ Darcy Ribeiro, Brasilia, DF - Brazil
[3] Univ Sao Paulo, Fac Med FMUSP, Dept Med Prevent, Sao Paulo, SP - Brazil
[4] Hosp Transplantes Euryclides Jesus Zerbini, Sao Paulo, SP - Brazil
Total Affiliations: 4
|
| Document type: | Journal article |
| Source: | Clinics; v. 72, n. 8, p. 499-509, AUG 2017. |
| Web of Science Citations: | 0 |
| Abstract | |
The aim of this study is to identify and characterize the health economic evaluations (HEEs) of diagnostic tests conducted in Brazil, in terms of their adherence to international guidelines for reporting economic studies and specific questions in test accuracy reports. We systematically searched multiple databases, selecting partial and full HEEs of diagnostic tests, published between 1980 and 2013. Two independent reviewers screened articles for relevance and extracted the data. We performed a qualitative narrative synthesis. Forty-three articles were reviewed. The most frequently studied diagnostic tests were laboratory tests (37.2%) and imaging tests (32.6%). Most were non-invasive tests (51.2%) and were performed in the adult population (48.8%). The intended purposes of the technologies evaluated were mostly diagnostic (69.8%), but diagnosis and treatment and screening, diagnosis, and treatment accounted for 25.6% and 4.7%, respectively. Of the reviewed studies, 12.5% described the methods used to estimate the quantities of resources, 33.3% reported the discount rate applied, and 29.2% listed the type of sensitivity analysis performed. Among the 12 cost-effectiveness analyses, only two studies (17%) referred to the application of formal methods to check the quality of the accuracy studies that provided support for the economic model. The existing Brazilian literature on the HEEs of diagnostic tests exhibited reasonably good performance. However, the following points still require improvement: 1) the methods used to estimate resource quantities and unit costs, 2) the discount rate, 3) descriptions of sensitivity analysis methods, 4) reporting of conflicts of interest, 5) evaluations of the quality of the accuracy studies considered in the cost-effectiveness models, and 6) the incorporation of accuracy measures into sensitivity analyses. (AU) | |
| FAPESP's process: | 12/22126-3 - Systematic review of economic evaluation studies developed in Brazil from 1980-2012 |
| Grantee: | Patricia Coelho de Soárez |
| Support Opportunities: | Regular Research Grants |