| Full text | |
| Author(s): |
Fumagalli, Fernando
[1]
;
Warratz, Svenja
[1]
;
Zhang, Shou-Kun
[1]
;
Rogge, Torben
[1]
;
Zhu, Cuiju
[1]
;
Stueckl, A. Claudia
[2]
;
Ackermann, Lutz
[1]
Total Authors: 7
|
| Affiliation: | [1] Georg August Univ, Inst Organ & Biomol Chem, Tammannstasse 2, D-37077 Gottingen - Germany
[2] Georg August Univ, Inst Anorgan Chem, Tammannstasse 4, D-37077 Gottingen - Germany
Total Affiliations: 2
|
| Document type: | Journal article |
| Source: | CHEMISTRY-A EUROPEAN JOURNAL; v. 24, n. 16, p. 3984-3988, MAR 15 2018. |
| Web of Science Citations: | 22 |
| Abstract | |
meta-Selective C-H alkylations of bioactive purine derivatives were accomplished by versatile ruthenium catalysis. Thus, the arene-ligand-free complex {[}Ru(OAc)(2)(PPh3)(2)] enabled remote C-H functionalizations with ample scope and excellent levels of chemo- and positional selectivities. Detailed experimental and computational mechanistic studies provided strong support for a facile C-H activation within a ruthenium(II/III) manifold. (AU) | |
| FAPESP's process: | 16/24448-9 - Ruthenium-catalyzed site selective C-H activation reactions in heteroarenes |
| Grantee: | Fernando Fumagalli |
| Support Opportunities: | Scholarships abroad - Research Internship - Doctorate |