| Full text | |
| Author(s): |
Matsumura, Erika
[1]
;
Matas, Carla Gentile
[1]
;
Leite Magliaro, Fernanda Cristina
[1]
;
Pedreno, Raquel Meirelles
[1]
;
Lorenzi-Filho, Geraldo
[2]
;
Gandolfi Sanches, Seisse Gabriela
[1]
;
Mamede Carvallo, Renata Mota
[1]
Total Authors: 7
|
| Affiliation: | [1] Univ Sao Paulo, Fac Med, Dept Fonoaudiol Fisioterapia & Terapia Ocupac, Sao Paulo, SP - Brazil
[2] Univ Sao Paulo, Fac Med, Inst Coracdo InCor, Lab Sono, Div Pneumol, Sao Paulo, SP - Brazil
Total Affiliations: 2
|
| Document type: | Journal article |
| Source: | Brazilian Journal of Otorhinolaryngology; v. 84, n. 1, p. 51-57, JAN-FEB 2018. |
| Web of Science Citations: | 1 |
| Abstract | |
Abstract Introduction Obstructive sleep apnea causes changes in normal sleep architecture, fragmenting it chronically with intermittent hypoxia, leading to serious health consequences in the long term. It is believed that the occurrence of respiratory events during sleep, such as apnea and hypopnea, can impair the transmission of nerve impulses along the auditory pathway that are highly dependent on the supply of oxygen. However, this association is not well established in the literature. Objective To compare the evaluation of peripheral auditory pathway and brainstem among individuals with and without obstructive sleep apnea. Methods The sample consisted of 38 adult males, mean age of 35.8 (±7.2), divided into four groups matched for age and Body Mass Index. The groups were classified based on polysomnography in: control (n = 10), mild obstructive sleep apnea (n = 11) moderate obstructive sleep apnea (n = 8) and severe obstructive sleep apnea (n = 9). All study subjects denied a history of risk for hearing loss and underwent audiometry, tympanometry, acoustic reflex and Brainstem Auditory Evoked Response. Statistical analyses were performed using three-factor ANOVA, 2-factor ANOVA, chi-square test, and Fisher's exact test. The significance level for all tests was 5%. Results There was no difference between the groups for hearing thresholds, tympanometry and evaluated Brainstem Auditory Evoked Response parameters. An association was observed between the presence of obstructive sleep apnea and changes in absolute latency of wave V (p = 0.03). There was an association between moderate obstructive sleep apnea and change of the latency of wave V (p = 0.01). Conclusion The presence of obstructive sleep apnea is associated with changes in nerve conduction of acoustic stimuli in the auditory pathway in the brainstem. The increase in obstructive sleep apnea severity does not promote worsening of responses assessed by audiometry, tympanometry and Brainstem Auditory Evoked Response. (AU) | |
| FAPESP's process: | 13/10281-7 - Obstructive sleep apnea: effect in the hearing pattern |
| Grantee: | Erika Matsumura |
| Support Opportunities: | Scholarships in Brazil - Master |