Panoramic and skull imaging may aid in the identification of multiple myeloma lesions

Author(s):Show less -

Faria, Karina-Morais ^{[1, 2]} ; Brandao, Thais-Bianca ^{[1, 2]} ; Silva, Wagner-Gomes ^{[1, 2]} ; Pereira, Juliana ^[3] ; Neves, Frederico-Sampaio ^[4] ; Alves, Marcelo-Correa ^[5] ; Shintaku, Werner-Harumiti ^[6] ; Lopes, Marcio-Ajudarte ^[1] ; Ribeiro, Ana-Carolina-Prado ^[2] ; Migliorati, Cesar-Augusto ^[6] ; Santos-Silva, Alan-Roger ^{[1, 2]}

Affiliation

^[1] Univ Campinas UNICAMP, Piracicaba Dent Sch, Semiol Area, Oral Diag Dept, Av Limeira 901, BR-13414903 Piracicaba, SP - Brazil

^[2] Univ Sao Paulo, Fac Med, ICESP, Dent Oncol Serv, Av Dr Arnaldo 251, BR-01246000 Sao Paulo, SP - Brazil

^[3] Univ Sao Paulo, Fac Med, ICESP, Hematol Serv, Av Dr Arnaldo 251, BR-01246000 Sao Paulo, SP - Brazil

^[4] Univ Fed Bahia, Div Oral Radiol, Dept Propedeut & Integrated Clin, Salvador, BA - Brazil

^[5] Univ Sao Paulo, Syst Analyst Tech Sect Informat, Luiz de Queiroz Coll Agr ESALQ, Av Padua Dias 11, BR-13418900 Piracicaba, SP - Brazil

^[6] UTHSC, Coll Dent, Dept Diagnost Sci & Oral Med, Union Ave 875, Memphis, TN 38103 - USA

• Document type: Journal article
• Source: MEDICINA ORAL PATOLOGIA ORAL Y CIRUGIA BUCAL; v. 23, n. 1, p. E38-E43, JAN 1 2018.
• Web of Science Citations: 1

Abstract

Background: The purpose of this study was to investigate the presence of punched-out lesions in craniofacial bones using three different radiographic protocols in a large cohort of patients. Material and Methods: One hundred fifty-five MM patients were evaluated using panoramic and skull (frontal and lateral) radiographs, which were performed in all patients at the time of MM diagnosis. The diagnostic potential for detecting punched-out lesions was compared among the radiographic techniques. Results: MM punched-out lesions were identified in 135 (87%) panoramic radiographs, 141 (91%) frontal and 144 (93%) lateral skull radiographs. Punched out-lesions were synchronously present in skull and jawbones in 129 (83.23 %) cases. The lesions were detected exclusively in skull in 18 (11.61%) cases and exclusively in jawbones in 6 (3.87%) cases. Punched out-lesion mainly affected the skull and the jawbones in a synchronous way (p<0.001) rather than separately. Conclusions: All investigated radiographic techniques (panoramic, frontal and lateral skull approaches) demonstrated high detection rates for MM punched-out lesions in craniofacial bones. Panoramic radiography may aid to the radiographic protocols to identify multiple myeloma bone lesions. (AU)

• FAPESP's process: 13/00429-7 - 2013 Annual Meeting (of The American Academy of Oral Medicine (AAOM)
• Grantee: Alan Roger dos Santos Silva
• Support Opportunities: Research Grants - Meeting - Abroad
• FAPESP's process: 12/06138-1 - A prospective study of radiation-induced trismus in patients with oral squamous cell carcinoma
• Grantee: Ana Carolina Prado Ribeiro e Silva
• Support Opportunities: Regular Research Grants
• FAPESP's process: 13/18402-8 - Evaluation of the direct effects of radiation on the enamel, dentin and dental pulp of head and neck cancer patients
• Grantee: Alan Roger dos Santos Silva
• Support Opportunities: Regular Research Grants