Association between hemodynamic activity and motor performance in six-month-old full-term and preterm infants: a functional near-infrared spectroscopy study

Author(s)

de Oliveira, Suelen Rosa ^[1] ; Cabral de Paula Machado, Ana Carolina ^[1] ; de Paula, Jonas Jardim ^[1] ; Paiva de Moraes, Paulo Henrique ^[1] ; Silverio Nahin, Maria Juliana ^[1] ; Magalhaes, Livia de Castro ^[2] ; Novi, Sergio L. ^[3] ; Mesquita, Rickson C. ^[3] ; de Miranda, Debora Marques ^[1] ; Ferrarez Bouzada, Maria Candida ^[1]

Affiliation

^[1] Univ Fed Minas Gerais, Sch Med, Belo Horizonte, MG - Brazil

^[2] Univ Fed Minas Gerais, Sch Phys Educ Physiotherapy & Occupat Therapy, Belo Horizonte, MG - Brazil

^[3] Univ Estadual Campinas, Inst Phys, Campinas, SP - Brazil

• Document type: Journal article
• Source: NEUROPHOTONICS; v. 5, n. 1 JAN-MAR 2018.
• Web of Science Citations: 1

Abstract

This study aimed to assess task-induced activation in motor cortex and its association with motor performance in full-term and preterm born infants at six months old. A cross-sectional study of 73 sixmonth- old infants was conducted (35 full-term and 38 preterm infants). Motor performance was assessed using the Bayley Scales of Infant Development third edition-Bayley-III. Brain hemodynamic activity during motor task was measured by functional near-infrared spectroscopy (fNIRS). Motor performance was similar in full-term and preterm infants. However, differences in hemodynamic response were identified. Full terms showed a more homogeneous unilateral and contralateral activated area, whereas in preterm-born the activation response was predominantly bilateral. The full-term group also exhibited a shorter latency for the hemodynamic response than the preterm group. Hemodynamic activity in the left sensorimotor region was positively associated with motor performance measured by Bayley-III. The results highlight the adequacy of fNIRS to assess differences in task-induced activation in sensorimotor cortex between groups. The association between motor performance and the hemodynamic activity require further investigation and suggest that fNIRS can become a suitable auxiliary tool to investigate aspects of neural basis on early development of motor abilities. (C) 2017 Society of Photo-Optical Instrumentation Engineers (SPIE) (AU)

• FAPESP's process: 12/02500-8 - Instrumentation and methodology development for cerebral oxygenation, blood flow and metabolic monitoring with diffuse optical spectroscopies
• Grantee: Rickson Coelho Mesquita
• Support Opportunities: Research Grants - Young Investigators Grants
• FAPESP's process: 13/07559-3 - BRAINN - The Brazilian Institute of Neuroscience and Neurotechnology
• Grantee: Fernando Cendes
• Support Opportunities: Research Grants - Research, Innovation and Dissemination Centers - RIDC