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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Colorimetric paper-based device for gaseous hydrogen cyanide quantification based on absorbance measurements

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Author(s):
da Silveira Petruci, Joao Flavio [1, 2] ; Hauser, Peter C. [2] ; Cardoso, Arnaldo Alves [1]
Total Authors: 3
Affiliation:
[1] Sao Paulo State Univ UNESP, Dept Analyt Chem, BR-14800970 Araraquara, SP - Brazil
[2] Univ Basel, Dept Chem, Spitalstr 51, CH-4056 Basel - Switzerland
Total Affiliations: 2
Document type: Journal article
Source: SENSORS AND ACTUATORS B-CHEMICAL; v. 268, p. 392-397, SEP 1 2018.
Web of Science Citations: 9
Abstract

Hydrogen cyanide is a highly toxic compound employed for applications such as electroplating, production of organic solvents, fish stunning, and even as a chemical weapon. In this work, we describe a new microfluidic paper-based assay for selective cyanide determination, based on the reaction of the cyanide anion with palladium dimethylglyoximate (DMG) followed by colorimetric reaction of DMG with nickel. Quantification was performed by measuring the absorbance of light passing through the paper, employing an LED emitting at 525 nm and a log ratio amplifier circuit emulating Lambert-Beer's law. This offers an alternative to the smartphone-based methodologies for signal treatment usually employed in colorimetric mu PAD-based methods The technique enabled linear calibration within the range 100-500 ppb of HCN, as well as a detection limit of 10 ppb for HCN in gaseous samples. The sampling time used for this concentration range was 5 min. The method was also tested for the quantification of cyanide in aqueous samples by adding H3PO4 to the sample, followed by exposure of the paper sensor to the gaseous HCN generated. A detection limit of 1 mu M was achieved, which makes the method also suitable for detection of cyanide in liquid samples. (C) 2018 Elsevier B.V. All rights reserved. (AU)

FAPESP's process: 15/23265-5 - Miniaturized equipment based on change of optical property and management by free hardware for determination of trace gases in the atmosphere
Grantee:Arnaldo Alves Cardoso
Support Opportunities: Regular Research Grants
FAPESP's process: 16/16830-0 - Miniaturized platform for gaseous sensing using LED's and microfluidic paper analytical devices
Grantee:João Flávio da Silveira Petruci
Support Opportunities: Scholarships abroad - Research Internship - Post-doctor