Wuhan large pig roundworm virus identified in human feces in Brazil

Author(s):Show less -

Luchs, Adriana ^[1] ; Leal, Elcio ^[2] ; Komninakis, Shirley Vasconcelos ^{[3, 4]} ; de Padua Milagres, Flavio Augusto ^{[5, 6, 7]} ; Brustulin, Rafael ^{[5, 6]} ; Rodrigues Teles, Maria da Aparecida ^[5] ; Gill, Danielle Elise ^[8] ; Deng, Xutao ^{[9, 10]} ; Delwart, Eric ^{[9, 10]} ; Sabino, Ester Cerdeira ^{[8, 7]} ; da Costa, Antonio Charlys ^[8]

Affiliation

^[1] Adolfo Lutz Inst, Virol Ctr, Enter Dis Lab, Av Dr Arnaldo 355, BR-01246902 Sao Paulo, SP - Brazil

^[2] Fed Univ Para, Inst Biol Sci, Belem, Para - Brazil

^[3] Fac Med ABC, Postgrad Program Hlth Sci, Santo Andre - Brazil

^[4] Univ Fed Sao Paulo, Retrovirol Lab, Sao Paulo, SP - Brazil

^[5] Publ Hlth Lab Tocantins State LACEN TO, Palmas - Brazil

^[6] Fed Univ Tocantins, Palmas, Tocantins - Brazil

^[7] Univ Sao Paulo, Fac Med, LIM 46, Sao Paulo - Brazil

^[8] Univ Sao Paulo, Inst Trop Med, Av Dr Eneas de Carvalho Aguiar 470, BR-05403000 Sao Paulo, SP - Brazil

^[9] Blood Syst Res Inst, San Francisco, CA - USA

^[10] Univ Calif San Francisco, Dept Lab Med, San Francisco, CA 94143 - USA

• Document type: Journal article
• Source: VIRUS GENES; v. 54, n. 3, p. 470-473, JUN 2018.
• Web of Science Citations: 2

Abstract

We report here the complete genome sequence of a bipartite virus, herein denoted WLPRV/human/BRA/TO-34/201, from a sample collected in 2015 from a two-year-old child in Brazil presenting acute gastroenteritis. The virus has 98-99% identity (segments 2 and 1, respectively) with the Wuhan large pig roundworm virus (unclassified RNA virus) that was recently discovered in the stomachs of pigs from China. This is the first report of a Wuhan large pig roundworm virus detected in human specimens, and the second genome described worldwide. However, the generation of more sequence data and further functional studies are required to fully understand the ecology, epidemiology, and evolution of this new unclassified virus. (AU)

• FAPESP's process: 15/12944-9 - Investigating the evoltution of animal rotavirus strains infecting humans
• Grantee: Adriana Luchs
• Support Opportunities: Regular Research Grants
• FAPESP's process: 17/00021-9 - Viral metagenomics to track, explain and predict the transmission and spatiotemporal spread of Dengue and Chikungunya viruses in Brazil
• Grantee: Antonio Charlys da Costa
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• FAPESP's process: 16/01735-2 - Viral metagenomics to track, explain and predict the transmission and spatiotemporal spread of Dengue and Chikungunya viruses in Brazil
• Grantee: Ester Cerdeira Sabino
• Support Opportunities: Regular Research Grants