| Full text | |
| Author(s): |
Vinícius de Godoi Contessoto
;
Antonio Bento de Oliveira Junior
[2]
;
Jorge Chahine
[3]
;
Ronaldo Junio de Oliveira
[4]
;
Vitor Barbanti Pereira Leite
[5]
Total Authors: 5
|
| Document type: | Journal article |
| Source: | Revista Brasileira de Ensino de Física; v. 40, n. 4 2018-06-18. |
| Abstract | |
Abstract This work aims to introduce students of physics and related areas to the problem of protein folding. Proteins are biological macromolecules of great importance to living things. The understanding of how this macromolecule finds a three-dimensional and functional structure, using the information present in a linear sequence of different amino acids, is a relevant question which involves researchers from different areas of knowledge. This work discusses the importance and the main properties of proteins and presents a brief history of protein folding studies and how these works converge to the Energy Landscape theory. There are described some theoretical and computational models from analytical approaches to the development of the Structure-Based Models for simulations. Here it is also presented and discussed some expected results for each used model. (AU) | |
| FAPESP's process: | 16/19766-1 - Biological macromolecules energy landscapes with applications in biotechnology and in biomedicine |
| Grantee: | Vitor Barbanti Pereira Leite |
| Support Opportunities: | Regular Research Grants |
| FAPESP's process: | 16/13998-8 - Rational evolution by computational methods applied to predict mutations in enzymes to biofuels production |
| Grantee: | Vinícius de Godoi Contessoto |
| Support Opportunities: | Scholarships in Brazil - Post-Doctoral |
| FAPESP's process: | 14/06862-7 - Computational studies in protein folding and enzymes engineering involved in bioethanol production |
| Grantee: | Vitor Barbanti Pereira Leite |
| Support Opportunities: | Regular Research Grants |
| FAPESP's process: | 17/09662-7 - Rational Evolution by Computational Methods Applied in Enzymes Related to Bioethanol Production |
| Grantee: | Vinícius de Godoi Contessoto |
| Support Opportunities: | Scholarships abroad - Research Internship - Post-doctor |