Influence of dentin pretreatment with 2.5% titanium tetrafluoride on inhibiting caries at the tooth-restoration interface in situ

Author(s)

Bridi, Enrico Coser ^[1] ; Botelho do Amaral, Flavia Lucisano ^[1] ; Gomes Franca, Fabiana Mantovani ^[1] ; Turssi, Cecilia Pedroso ^[1] ; Basting, Roberta Tarkany ^[1]

Affiliation

^[1] Sao Leopoldo Mandic Inst & Dent Res Ctr, Rua Jose Rocha Junqueira 13, BR-13045755 Campinas, SP - Brazil

• Document type: Journal article
• Source: ARCHIVES OF ORAL BIOLOGY; v. 86, p. 51-57, FEB 2018.
• Web of Science Citations: 4

Abstract

Objective: Investigate the effects of dentin pretreatment with 2.5% titanium tetrafluoride (TiF4) aqueous solution followed by two-step self-etching (CLE/Clearfil SE Bond) and one-step self-etching adhesive systems (SBU/Single Bond Universal) on carious lesion inhibition at the tooth-restoration interface using an in situ model. Design: Sixty-four cavities at the enamel-dentin junction of dental fragments were randomly distributed according to groups (n = 16): 1) TiF4 + CLE; 2) TiF4 + SBU; 3) CLE; 4) SBU. Cavities were restored using resin composite, and placed in intraoral palatal devices used by 16 volunteers for 21 days, to induce caries formation in situ. The fragments were then ground-flat to perform Knoop microhardness tests. Nine indentations were performed on each enamel and dentin substrate, subjacent to the restoration. Analysis of variance and Tukey's test were applied. Results: Enamel: groups receiving TiF4 dentin pretreatment (regardless of adhesive system and tooth-restoration interface distance) presented higher hardness means at a depth of 25 mu m from the outer tooth surface (p < 0.0001). Dentin: groups receiving CLE presented higher means when applying TiF4 pretreatment, whereas groups restored with SBU presented higher means without pretreatment (p = 0.0003). Conclusions: Dentin pretreatment with TiF4 inhibited demineralization of the enamel interface in situ, regardless of the adhesive, and TiF4 pretreatment followed by CLE application showed higher potential for inhibiting dentin demineralization at the interface. (AU)

• FAPESP's process: 14/05622-2 - In situ evaluation of caries lesions inhibition at the interface tooth/restoration and in vitro evaluation of the longevity of dentin bond after dentin pretreatment with titanium tetrafluoride and self-etching adhesive systems
• Grantee: Enrico Coser Bridi
• Support Opportunities: Scholarships in Brazil - Doctorate