| Full text | |
| Author(s): |
Soares, Ciro Dantas
[1]
;
Rocha, Breno Amaral
[2]
;
Ribeiro Paranaiba, Livia Maris
[3, 4]
;
de Melo-Filho, Mario Rodrigues
[2, 3]
;
Jorge, Jacks
[1]
;
Freire de Carvalho, Maria Goretti
[5]
;
de Almeida, Oslei Paes
[1]
Total Authors: 7
|
| Affiliation: | [1] Univ Estadual Campinas, Piracicaba Dent Sch, Ave Limeira 901, BR-13414903 Piracicaba, SP - Brazil
[2] Santa Casa Hosp, Oncol Dent Serv, Montes Claros, MG - Brazil
[3] Univ Montes Claros, Sch Dent, Montes Claros, MG - Brazil
[4] Univ Estadual Montes Claros, Hlth Sci Program, Montes Claros, MG - Brazil
[5] Lab Citopatol, Private Serv, Natal, RN - Brazil
Total Affiliations: 5
|
| Document type: | Journal article |
| Source: | MEDICINE; v. 97, n. 13 MAR 2018. |
| Web of Science Citations: | 1 |
| Abstract | |
Rationale:Oral metastases occur more commonly in bone, but can also manifest in soft tissues and eventually resemble a reactive lesion. Few cases of oral metastases mimicking reactive lesions in soft tissues have been reported to date.Patient concerns:We report a metastasis of gastric carcinoma (GC) to the oral mucosa without bone involvement in a 43 yom clinically and microscopically mimicking a reactive lesion. The patient related that the lesion had 1 month of evolution, and the ulcerated area suggested the lesion was related to trauma.Diagnoses:The histopathological examination of the lesion revealed an exuberant granulation tissue with few neoplastic cells, and the initial diagnosis of pyogenic granuloma was considered. In a second analysis, clusters of clear cells morphologically similar to degenerating mucous cells or macrophages, positive for Cytokeratin (CK)-20, and CDX2 were found. At the moment, it was confirmed the presence of a primary GC in the patient.Interventions:A palliative radiotherapy/chemotherapy was started.Outcomes:However, the patient died 3 months after the diagnosis of oral metastasis.Lessons:This report highlights the importance of careful clinical and microscopic examinations in cases of oral metastasis that may mimic a reactive lesion. (AU) | |
| FAPESP's process: | 15/25905-1 - Akt, COX-2, RUNX1 and MMPs expression in metastatic melanomas and Biotechnology prospection of molecules with antineoplastic activity |
| Grantee: | Ciro Dantas Soares |
| Support Opportunities: | Scholarships in Brazil - Doctorate |
| FAPESP's process: | 17/16102-8 - Akt, COX-2, RUNX1 and MMPs expression in metastatic melanomas |
| Grantee: | Jacks Jorge Junior |
| Support Opportunities: | Regular Research Grants |